×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [9]
上海中医药大学 [5]
山东大学 [4]
复旦大学上海医学院 [4]
中国医学科学院 北京... [4]
北京大学 [3]
更多...
内容类型
期刊论文 [44]
发表日期
2021 [1]
2020 [3]
2019 [6]
2018 [1]
2017 [2]
2016 [3]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共44条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:
Pan, Lulu
;
Guo, Shuang
;
Chen, Xiaoyan
;
Jiang, Xiangrui
;
Shen, Jingshan
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/07/01
TPNI71
Metabolism
UPLC/Q-TOF MS
High-resolution mass spectrometry
Metabolite identification
Rapid Identification of Berberine Metabolites in Rat Plasma by UHPLC-Q-TOF-MS
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 10
作者:
Jiang, Jiebing
;
Li, Dan
;
Li, Yan
;
Xu, Peng
;
Xu, Chen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
berberine
metabolite identification
high resolution mass spectrometry
rat plasma
Metabolite identification of tanshinol borneol ester in rats by high-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight mass spectrometry.
期刊论文
Biomedical chromatography : BMC, 2019, 卷号: 33, 页码: e4438
作者:
Wang Jie
;
Ma Cuicui
;
Li Qiannan
;
Wang Xing
;
Yang Yang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/11/19
metabolic profile
metabolite identification
DBZ
HPLC-ESI-Q-TOF-MS
Metabolism of vesatolimod in rat, dog, and human liver microsomes: Metabolic stability assessment, metabolite identification, and interspecies comparison
期刊论文
Drug Testing and Analysis, 2019, 卷号: Vol.11 No.2, 页码: 240-249
作者:
Wen Li
;
Jing Zhang
;
Yanping Wang
;
Fangdi Hu
;
Yinghua Zhang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
interspecies
comparison
metabolic
stability
metabolite
identification
Vesatolimod
Metabolite identification of tanshinol borneol ester in rats by high-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight mass spectrometry.
期刊论文
Biomedical chromatography, 2019, 卷号: Vol.33 No.3, 页码: e4438
作者:
Wang Jie
;
Ma Cuicui
;
Li Qiannan
;
Wang Xing
;
Yang Yang
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/17
metabolic profile
metabolite identification
DBZ
HPLC-ESI-Q-TOF-MS
Metabolite identification of tanshinol borneol ester in rats by high‐performance liquid chromatography combined with electrospray ionization quadrupole time‐of‐flight mass spectrometry
期刊论文
Biomedical Chromatography, 2019, 卷号: Vol.33 No.3
作者:
Jie Wang
;
Cuicui Ma
;
Qiannan Li
;
Xing Wang
;
Yang Yang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/17
DBZ
HPLC‐ESI‐Q‐TOF‐MS
metabolic
profile
metabolite
identification
©版权所有 ©2017 CSpace - Powered by
CSpace