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科研机构
复旦大学上海医学院 [4]
金属研究所 [3]
清华大学 [2]
上海药物研究所 [2]
中国医学科学院 北京... [2]
北京大学 [1]
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期刊论文 [21]
发表日期
2018 [2]
2016 [3]
2015 [2]
2014 [1]
2013 [3]
2012 [1]
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Enriched environment improves working memory impairment of mice with traumatic brain injury by enhancing histone acetylation in the prefrontal cortex
期刊论文
PEERJ, 2018, 卷号: 6
作者:
Wang, Xin
;
Meng, Zhaoxiang
;
Wang, Jibing
;
Zhou, Hongyu
;
Wu, Yi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Traumatic brain injury
CREB binding protein (CBP)
Acetylation homeostasis
Choline acetyltransferase
Working memory
Enriched environment
Enriched environment improves working memory impairment of mice with traumatic brain injury by enhancing histone acetylation in the prefrontal cortex
期刊论文
PeerJ, 2018, 卷号: Vol.6, 页码: e6113
作者:
Xin Wang
;
Zhaoxiang Meng
;
Jibing Wang
;
Hongyu Zhou
;
Yi Wu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
Traumatic
brain
injury
CREB
binding
protein
(CBP)
Acetylation
homeostasis
Choline
acetyltransferase
Working
memory
Enriched
environment
Enriched environment improves post-stroke cognitive impairment in mice by potential regulation of acetylation homeostasis in cholinergic circuits
期刊论文
BRAIN RESEARCH, 2016, 卷号: 1650
作者:
Wang, Xiaohong
;
Zhang, Xiaobin
;
Wu, Di
;
Gu, Xin
;
Shen, Feiyang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Post-stroke cognitive impairment
Choline acetyltransferase
Enriched environment
Histone acetylation homeostasis
Phosphorylated CAMP response element binding protein (p-CREB)
CREB binding protein (CBP)
Enriched environment improves post-stroke cognitive impairment in mice by potential regulation of acetylation homeostasis in cholinergic circuits
期刊论文
Brain research, 2016, 卷号: 1650, 页码: 232-242
作者:
Wang Xin[1]
;
Chen Aiguo[2]
;
Wu Honghai[3]
;
Ye Min[4]
;
Cheng Hong[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/26
CREB binding protein (CBP)
Choline acetyltransferase
Enriched environment
Histone acetylation homeostasis
Phosphorylated cAMP response element binding protein (p-CREB)
Post-stroke cognitive impairment
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:
Chu, Shifeng
;
Liu, Shaolin
;
Duan, Wenzhen
;
Cheng, Yong
;
Jiang, Xueying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Chirality
Clausenamide
Dementia
Long-term potentiation
Signaling pathway
Calcium
6-OHDA
6-hydroxyldopamine
ACE
acetylcholinesterase
ACh
acetylcholine
AD
Alzheimer's disease
AUC0–12 h
0–12 h area under curve
APP
amyloid precursor protein
APV
R-2-amino-5-phosphonopentanoate
AUC0−∝
whole area under curve
BBB
blood–brain barrier
BDNF
brain-derived neurotrophic factor
CaM
calmodulin
CaMKII
calmodulin kinase II
ChAT
choline acetyltransferase
CREB
cAMP responding element binding
CHM
Chinese herbal medicine
clau
clausenamide
CL
clearance
Cmax
maximum concentration
CDK-5
cyclin-dependent kinase-5
DM
diabetes mellitus
DAG
diacylglycerol
ER
endoplasmic reticulum
ERK
extracellular signal-regulated kinases
GSK-3
glycogen synthase kinase-3
IP3
inositol triphosphate
LTP
long term potentiation
MWM
Morris water maze
NGF
nerve growth factor
NMDA
N-Methyl-D-aspartate
D
nNOS
neural nitric oxide synthase
PAT
passive avoidance tasks
Pir
piracetam
PLC
phospholipase C
PP1
phosphate 1
PKC
protein kinase C
tmax
time of peak concentration
t1/2α
absorption half-life
t1/2β
elimination half-life
Tau
microtubule-associated proteins
TCM
traditional Chinese medicine
Vd
apparent volume of distribution
VDCC
voltage-dependent calcium channel
Use of C-11-Choline positron emission tomography/computed tomography to investigate the mechanism of choline metabolism in lung cancer
期刊论文
Molecular medicine reports, 2015, 卷号: 11, 期号: 5, 页码: 3285-3290
作者:
Huang, Zhaoqin
;
Rui, Jun
;
Li, Xin
;
Meng, Xiangjiao
;
Liu, Qingwei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
lung cancer
choline acetyltransferase
choline kinase
C-11-Choline
positron emission tomography
The interrelationship between cholinergic pathway in the magnocellular paraventricular nucleus and natriuresis
期刊论文
2015, 卷号: 34, 期号: 3, 页码: 293-299
作者:
Wang, Chunyan
;
Wang, Min
;
Zhang, Heng-ai
;
Deng, Xijia
;
Wang, Pengxu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
Carbachol-natriuresis-choline
Acetyltransferase-magnocellular
Paraventricular nucleus-proximal convoluted tubule
Effects of pregnenolone intervention on the cholinergic system and synaptic protein 1 in aged rats
期刊论文
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2014, 卷号: 124, 期号: 2
作者:
Bu, Jimei
;
Zu, Hengbing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
pregnenolone
choline acetyltransferase
synaptic protein 1
acetylcholinesterase
memory
Human umbilical cord mesenchymal stem cells derived from Wharton"s jelly differentiate into cholinergic-like neurons in vitro
期刊论文
NEUROSCIENCE LETTERS, 2013, 卷号: 532
作者:
Zhou, Li
;
Zhao, Hui
;
Li, Shu-lei
;
Liang, Jun
;
Wu, Shan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Alzheimer"s disease
Choline acetyltransferase
Umbilical cord
Wharton"s jelly
Mesenchymal stem cells
Effects of puerarin on cholinergic enzymes in the brain of ovariectomized guinea pigs
期刊论文
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2013, 卷号: 123, 期号: 11
作者:
Zhang, Yanping
;
Chen, Yan
;
Shan, Ye
;
Wang, Dandan
;
Zhu, Cuiqing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Puerarin
ovariectomy
guinea pig
choline acetyltransferase
acetylcholinesterase
beta-amyloid
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