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科研机构
湖南大学 [13]
暨南大学 [1]
内容类型
期刊论文 [14]
发表日期
2019 [8]
2018 [6]
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Small molecules as inhibitors of PCSK9: Current status and future challenges
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Shengtao Xu
;
Shanshan Luo
;
Zheying Zhu
;
Jinyi Xu
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/13
PCSK9
protein
Inhibitor
Small-molecule
LDL-C
Hypercholesterolemia
Natural
products
Patent
Small molecules as inhibitors of PCSK9: Current status and future challenges
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Xu, Shengtao
;
Luo, Shanshan
;
Zhu, Zheying
;
Xu, Jinyi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
PCSK9 protein
Inhibitor
Small-molecule
LDL-C
Hypercholesterolemia
Natural products
Patent
Discovery of Novel Quinoline–Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity
期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.2, 页码: 993-1013
作者:
Wenlong Li
;
Feijie Xu
;
Wen Shuai
;
Honghao Sun
;
Hong Yao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/17
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: Vol.167, 页码: 485-498
作者:
Hong Yao
;
Feijie Xu
;
Guangyu Wang
;
Shaowen Xie
;
Wenlong Li
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/17
Anticancer
Deguelin
Heat
shock
protein
90
Structure
simplification
Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors
期刊论文
European Journal of Medicinal Chemistry, 2019
作者:
Hong Yao
;
Feijie Xu
;
Guangyu Wang
;
Shaowen Xie
;
Wenlong Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/17
Heat
shock
protein
90
Deguelin
Structure
simplification
Anticancer
Small molecules as inhibitors of PCSK9: Current status and future challenges.
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.162, 页码: 212-233
作者:
Xu, Shengtao
;
Luo, Shanshan
;
Zhu, Zheying
;
Xu, Jinyi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
SMALL
molecules
*PROPROTEIN
convertases
*SUBTILISINS
*PHARMACEUTICAL
chemistry
*DRUG
derivatives
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site
期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.163, 页码: 428-442
作者:
Wenlong Li
;
Wen Shuai
;
Honghao Sun
;
Feijie Xu
;
Yi Bi
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/13
Quinoline
Indole
Microtubule
Tubulin
inhibitor
Colchicine
binding
site
Antitumor
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site
期刊论文
Bioorganic Chemistry, 2019, 卷号: Vol.85, 页码: 49-59
作者:
Wenlong Li
;
Honghao Sun
;
Feijie Xu
;
Wen Shuai
;
Jie Liu
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/13
Tubulin
inhibitor
Vinyl
sulfone
Indole
Colchicine
site
Drug-likeness
Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies
期刊论文
2018, 卷号: 9, 期号: 10, 页码: 1030
作者:
Yao, Hong[1,2]
;
Wei, Guoxiang[1,2]
;
Liu, Yanpeng[1,2]
;
Yao, Hequan[1,2]
;
Zhu, Zheying[3]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Discovery of Novel Quinoline-Chalcone Derivatives as Potent Anti-tumor Agents with Microtubule Polymerization Inhibitory Activity.
期刊论文
Journal of medicinal chemistry, 2018
作者:
Li Wenlong
;
Xu Feijie
;
Shuai Wen
;
Sun Honghao
;
Yao Hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/26
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