Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site | |
Wenlong Li; Honghao Sun; Feijie Xu; Wen Shuai; Jie Liu; Shengtao Xu; Hequan Yao; Cong Ma; Zheying Zhu; Jinyi Xu | |
刊名 | Bioorganic Chemistry |
2019 | |
卷号 | Vol.85页码:49-59 |
关键词 | Tubulin inhibitor Vinyl sulfone Indole Colchicine site Drug-likeness |
ISSN号 | 0045-2068 |
URL标识 | 查看原文 |
公开日期 | [db:dc_date_available] |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/4606536 |
专题 | 湖南大学 |
作者单位 | 1.b State Key Laboratory of Chemical Biology and Drug Discovery, and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Kowloon, Hong Kong 2.Division of Molecular Therapeutics & Formulation, School of Pharmacy, The University of Nottingham, University Park Campus, Nottingham N 3.2RD, UK a State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China |
推荐引用方式 GB/T 7714 | Wenlong Li,Honghao Sun,Feijie Xu,et al. Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site[J]. Bioorganic Chemistry,2019,Vol.85:49-59. |
APA | Wenlong Li.,Honghao Sun.,Feijie Xu.,Wen Shuai.,Jie Liu.,...&Jinyi Xu.(2019).Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site.Bioorganic Chemistry,Vol.85,49-59. |
MLA | Wenlong Li,et al."Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site".Bioorganic Chemistry Vol.85(2019):49-59. |
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