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Anxiolytic Effect of Alcohol-Water Extracted Suanzaoren-Wuweizi Herb-Pair by Regulating ECS-BDNF-ERK Signaling Pathway Expression in Acute Restraint Stress Male Rats 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2020, 卷号: 2020, 页码: 13
作者:  Zhao, Cheng-Bo-Wen;  Liu, Jie;  Shi, Jin-Li;  Wang, Shao-Nan;  Ding, Yong-Sheng
收藏  |  浏览/下载:70/0  |  提交时间:2020/08/03
Structural elucidation of a pectin from roots of Polygala tenuifolia and its neuritogenesis inducing activity in PC12 cells 期刊论文
CARBOHYDRATE POLYMERS, 2020, 卷号: 236, 页码: 9
作者:  Zeng, Hui;  Huang, Lulin;  Tao, Hong;  Zhang, Yiwen;  Ding, Kan
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
The Dopamine Receptor D3 Regulates Lipopolysaccharide-Induced Depressive-Like Behavior in Mice 期刊论文
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2018, 卷号: 21, 页码: 448-460
作者:  Wang, Jing;  Jia, Yuwei;  Li, Guodong;  Wang, Biao;  Zhou, Ting
收藏  |  浏览/下载:13/0  |  提交时间:2019/11/26
Region-Dependent Alterations in Cognitive Function and ERK1/2 Signaling in the PFC in Rats after Social Defeat Stress 期刊论文
NEURAL PLASTICITY, 2018, 页码: 1-12
作者:  Wang, Qiong;  Shao, Feng;  Wang, Weiwen
收藏  |  浏览/下载:36/0  |  提交时间:2018/07/02
Genistein Ameliorates Scopolamine-Induced Amnesia in Mice Through the Regulation of the Cholinergic Neurotransmission, Antioxidant System and the ERK/CREB/BDNF Signaling 期刊论文
2018, 卷号: 9, 页码: 1153
作者:  Lu, Cong;  Wang, Yan;  Xu, Teng;  Li, Qi;  Wang, Donghui
收藏  |  浏览/下载:10/0  |  提交时间:2020/01/03
Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence 期刊论文
NEURAL PLASTICITY, 2017
Zhang, Yu; Shao, Feng; Wang, Qiong; Xie, Xi; Wang, Weiwen
收藏  |  浏览/下载:7/0  |  提交时间:2017/12/03
Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence 期刊论文
NEURAL PLASTICITY, 2017, 期号: 0, 页码: 1-11
作者:  Zhang, Yu;  Shao, Feng;  Wang, Qiong;  Xie, Xi
收藏  |  浏览/下载:19/0  |  提交时间:2017/03/28
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  
复方抗焦虑胶囊对急性应激大鼠的抗焦虑作用及对大鼠脑内ERK/CREB信号通路和BDNF表达的影响 期刊论文
中国药理学通报, 2015, 卷号: 31, 期号: 11, 页码: 1614-1619
作者:  吕跃玮;  刘洁;  史淑宁;  郭建友;  刘勇
收藏  |  浏览/下载:48/0  |  提交时间:2016/09/07
Dysregulation of neurotrophic and inflammatory systems accompanied by decreased CREB signaling in ischemic rat retina 期刊论文
EXPERIMENTAL EYE RESEARCH, 2014, 卷号: 125, 页码: 156-163
作者:  Guo, Xian Jun;  Tian, Xue Song;  Ruan, Zhi;  Chen, Yu Ting;  Wu, Lei
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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