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Preparation and evaluation of PEGylated asiatic acid nanostructured lipid carriers on anti-fibrosis effects 期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2020, 卷号: 46, 期号: 1, 页码: 57-69
作者:  Chen, Xiaoxiao;  Zhang, Yawen;  Zhao, Pengfei;  Chen, Yan;  Zhou, Yunli
收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01
The intestinal absorption properties of flavonoids in Hippophae rhamnoides extracts by an in situ single-pass intestinal perfusion model 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 1
作者:  Xin, Lei;  Liu, Xiao-Hui;  Yang, Jun;  Shen, Hong-Yi;  Ji, Guang
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05
Use of fluorescein isothiocyanate isomer I to study the mechanism of intestinal absorption of fucoidan sulfate in vivo and in vitro 期刊论文
BIOPHARMACEUTICS & DRUG DISPOSITION, 2018, 卷号: 39, 期号: 6, 页码: 298-307
作者:  Zhang, E.;  Chu, Fulong;  Xu, Lixu;  Liang, Hao;  Song, Shuliang
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/11
Evaluation of the cytotoxicity and intestinal absorption of a self-emulsifying drug delivery system containing sodium taurocholate 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 106
作者:  Liu, Jianguo;  Gao, Hang;  Wang, Miao;  Sun, Dandan;  Sun, Shilin
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05
在体单向肠灌流模型研究绞股蓝皂苷的肠吸收特性 Intestinal absorption of gypenosides in rats by single pass perfusion in situ 期刊论文
2017, 卷号: 37, 页码: 1129-1133
作者:  喻樊[1,2,3,4];  汤新慧[1];  周姝婷[2]
收藏  |  浏览/下载：4/0  |  提交时间：2019/11/30
Absorption characteristics of the total alkaloids from Mahonia bealei in an in situ single-pass intestinal perfusion assay 期刊论文
2014, 卷号: 12, 期号: [db:dc_citation_issue], 页码: 554
作者:  Sun Yu-He[1];  He Xin[2];  Yang Xiao-Lin[3];  Dong Cui-Lan[4];  Zhang Chun-Feng[1]
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Intestinal Absorptive Transport of Genkwanin from Flos genkwa Using a Single-Pass Intestinal Perfusion Rat Model 期刊论文
2014, 卷号: 42, 期号: [db:dc_citation_issue], 页码: 349
作者:  Jiang, Cui-Ping[1];  He, Xin[2];  Yang, Xiao-Lin[3];  Zhang, Su-Li[1];  Li, Hui[1]
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03
Absorption characteristics of the bealei in an in situ single-pass total alkaloids from Mahonia intestinal perfusion assay 期刊论文
2014, 卷号: 12, 期号: 7, 页码: 554
作者:  SUN Yu-He[1];  HE Xin[2];  YANG Xiao-Lin[3];  DONG Cui-Lan[4];  ZHANG Chun-Feng[1]
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17
Mechanisms of microemulsion enhancing the oral bioavailability of puerarin: comparison between oil-in-water and water-in-oil microemulsions using the single-pass intestinal perfusion method and a chylomicron flow blocking approach 期刊论文
International Journal of Nanomedicine, 2013, 卷号: 8, 期号: 1, 页码: 4415-4426
作者:  Tang, Tian-Tian;  Hu, Xiong-Bin;  Liao, De-Hua;  Liu, Xin-Yi;  Xiang, Da-Xiong*
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
The purpose of the present work was to determine the mechanisms by which microemulsions (MEs) enhance the oral bioavailability of puerarin. The in situ perfusion method was used in rats to study the absorption mechanisms of an oil-in-water (O/W) microemulsion (O/W-ME) and a water-in-oil (W/O) microemulsion (W/O-ME). The possibility of lymphatic transport of the MEs was investigated using a chylomicron flow blocking approach. The results for the absorption mechanisms in the stomach and intestines indicated that the absorption characteristics of the O/W-ME and W/O-ME depend on the segment. The W/O-ME had higher internal membrane permeability than the O/W-ME. The results of the lymphatic transport analyses showed that both the O/W-ME and W/O-ME underwent lymphatic transport and that this pathway was a major contributor to the oral bioavailability of MEs. Furthermore  the type of ME can significantly affect the absorption of puerarin through the lymphatic system due to the oil content and the form of the microemulsion after oral administration. In conclusion  these data indicate that microemulsions are an effective and promising delivery system to enhance the oral bioavailability of poorly water-soluble drugs.  
Intestinal Permeability of Forskolin by In Situ Single Pass Perfusion in Rats 期刊论文
PLANTA MEDICA, 2012, 卷号: 78, 期号: 7
作者:  Liu, Zhen-Jun;  Jiang, Dong-bo;  Tian, Lu-Lu;  Yin, Jia-Jun;  Huang, Jian-Ming
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/19

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