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北京大学 [8]
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期刊论文 [22]
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Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 20
作者:
Hu, Huifang
;
Wang, Qing
;
Du, Jingwen
;
Liu, Zhijun
;
Ding, Yiluan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Aha1
NMR
dynamics
chaperone-like activity
α
-synuclein
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Lin, Guang-yao
;
Lin, Lin
;
Cai, Xiao-qing
;
Dai, An-tao
;
Zhu, Yue
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
RXFP4
INSL5
high-throughput screening
agonist
JK1
Serelaxin, recombinant human relaxin-2, for heart failure patients A systematic review and meta-analysis
期刊论文
2018, 卷号: 97, 期号: 25
作者:
Yu, Ling[1]
;
Cao, Lijuan[1]
;
Sun, Jing[2]
;
Li, Zhongyi[3]
;
Yao, Fengzhen[1]
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
Relaxin ameliorates high glucose‑induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway
期刊论文
Experimental and Therapeutic Medicine, 2018, 卷号: Vol.15 No.1, 页码: 691-698
作者:
Xiao Wei
;
Yuan Yang
;
Yin-Jiu Jiang
;
Jian-Ming Lei
;
Jing-Wen Guo
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
Transcriptional up-regulation of relaxin-3 by Nur77 attenuates -adrenergic agonist-induced apoptosis in cardiomyocytes
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: Vol.293 No.36, 页码: 14001-14011
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
transcription
factor
nuclear
receptor
cardiomyocyte
apoptosis
relaxin
isoprenoid
Nur77
relaxin-3
beta-adrenergic
receptor
transcriptional
regulator
promoter
A validated UPLC-MS/MS method coupled with protein precipitation and ion exchange solid phase extraction for the quantitation of porcine relaxin B29 in dog plasma and its application to a pharmacokinetic study
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2017, 卷号: 409, 期号: 28, 页码: 6559-6565
作者:
Su, Chong
;
Sun, Hui
;
Yang, Hong
;
Yin, Lei
;
Zhang, Jiwen
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  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Ion exchange solid phase extraction
LC-MS/MS
Porcine relaxin
Ultrahigh performance liquid chromatography
Effects of recombinant human relaxin-2 on hepatic stellate cell proliferation, synthesis of Collagen I, and mRNA expressions of TGF-β1 and CTGF in vitro
期刊论文
Journal of Xi'an Jiaotong University (Medical Sciences), 2017, 卷号: 38
作者:
Chen, Zhen
;
Xu, Jun-Wang
;
Yan, Su
;
Chen, Ke
;
Fan, Xiu-De
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/11/26
Connective tissue growth factor(CTGF)
Hepatic fibrosis
Hepatic stellate cell
Relaxin
Transforming growth factor(TGF)
Relaxin in paraventricular nucleus contributes to sympathetic overdrive and hypertension via PI3K-Akt pathway
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 103, 期号: [db:dc_citation_issue], 页码: 247-256
作者:
Sun, Hai-Jian
;
Chen, Dan
;
Han, Ying
;
Zhou, Ye-Bo
;
Wang, Jue-Jin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
Sympathetic
Hypertension
Relaxin
Vasopressin
Paraventricular nucleus
Bioactivity assay of porcine relaxin based on cAMP accumulation in THP-1 cells quantified by LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 卷号: 111, 页码: 320-323
作者:
Ren, Xiaohong
;
Wang, Caifen
;
Wu, Li
;
Li, Haiyan
;
Chi, Liandi
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Porcine relaxin
Bioactivity
cAMP
LC-MS/MS
ELISA
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