CORC

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CORC

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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
PHOSPHODIESTERASE INHIBITOR TYPE 5 (PDE 5), AND PREPARATION METHOD AND APPLICATION THEREOF 专利
申请日期: 2019-01-03, 公开日期: 2019-01-03
作者:  Lou HX(娄红祥);  Zheng HB(郑泓波);  Sun B(孙斌);  Li L(李琳);  Gao Y(高云)
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04
Alpha-blockers with or without phosphodiesterase type 5 inhibitor for treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: a systematic review and meta-analysis 期刊论文
2019, 卷号: 37, 期号: 1, 页码: 143-153
作者:  Zhang, Jianzhong;  Li, Xiao;  Yang, Bin;  Wu, Cheng;  Fan, Yanghua
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/03
吸入型药物重新用于哮喘治疗 科技动态
2018
作者:  yaoxn@llas.ac.cn
收藏  |  浏览/下载：14/0  |  提交时间：2018/07/05
Are phosphodiesterase type 5 inhibitors associated with increased risk of melanoma? 期刊论文
Medicine (Baltimore), 2018, 卷号: Vol.97 No.3, 页码: e9601
作者:  Shijian Feng;  Liang Zhou;  Qinyu Liu;  Qing He;  Banghua Liao
收藏  |  浏览/下载：5/0  |  提交时间：2019/02/25
The Association Between Phosphodiesterase Type 5 Inhibitor Use and Risk of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis 期刊论文
2018, 卷号: 6, 期号: 3, 页码: 185
作者:  Liu, Bing[1];  Zhu, Linxin[1];  Zhong, Jingxiang[1];  Zeng, Guohua[2,3,4];  Deng, Tuo[2,3,4]
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/13
Analysis of short-term treatment with the phosphodiesterase type 5 inhibitor tadalafil on long bone development in young rats 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2018, 卷号: 315, 期号: 4, 页码: E446-E453
作者:  Wang, Luqiang;  Jia, Haoruo;  Tower, Robert J.;  Levine, Michael A.;  Qin, Ling
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
A randomized clinical trial investigating treatment choice in Chinese men receiving sildenafil citrate and tadalafil for treating erectile dysfunction 期刊论文
2017, 卷号: 19, 期号: 4, 页码: 500-504
作者:  Bai, Wen-Jun;  Li, Hong-Jun;  Jin, Jian-Jun;  Xu, Wen-Ping;  Sebastian, Sorsaburu
收藏  |  浏览/下载：8/0  |  提交时间：2020/01/04

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