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大连化学物理研究所 [2]
北京大学 [1]
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期刊论文 [7]
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Geometric Structures and Electronic Properties of AlnV0/- (n=5-14) Clusters: Photoelectron Spectroscopy and Theoretical Calculations
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY C, 2019, 卷号: 123, 期号: 3, 页码: 1931-1938
作者:
Kuang, Xiaoyu
;
Xia, Xinxin
;
Zheng, Weijun
;
Zhang, Zeng-Guang
;
Xu, Hong-Guang
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浏览/下载:45/0
  |  
提交时间:2019/06/20
Geometric structures and electronic properties of alnv0/- (n=5-14) clusters: photoelectron spectroscopy and theoretical calculations
期刊论文
Journal of physical chemistry c, 2019, 卷号: 123, 期号: 3, 页码: 1931-1938
作者:
Xia, Xinxin
;
Zhang, Zeng-Guang
;
Xu, Hong-Guang
;
Xu, Xiling
;
Kuang, Xiaoyu
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  |  
浏览/下载:64/0
  |  
提交时间:2019/05/08
Competitive Inhibition Mechanism of Acetylcholinesterase without Catalytic Active Site Interaction: Study on Functionalized C-60 Nanoparticles via in Vitro and in Silico Assays
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 22, 页码: 18626-18638
作者:
Liu, Yanyan
;
Yan, Bing
;
Winkler, David A.
;
Fu, Jianjie
;
Zhang, Aigian
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  |  
浏览/下载:19/0
  |  
提交时间:2018/07/26
C-60 Nanoparticle
Acetylcholinesterase
Competitive Inhibition
Peripheral Anionic Site
Quantitative Nanostructure-activity Relationship
Molecular Docking
Site-directed Mutation
Multipotent AChE and BACE-1 inhibitors for the treatment of Alzheimer's disease: Design, synthesis and bio-analysis of 7-amino-1,4-dihydro-2H-isoquilin-3-one derivates
期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 138, 页码: 738-747
作者:
Zhao, Xiong-jie
;
Gong, Da-min
;
Jiang, Yu-ren*
;
Guo, Dong
;
Zhu, Yao
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  |  
浏览/下载:56/0
  |  
提交时间:2019/12/03
Alzheimer's disease
Acetylcholinesterase
β-secretase
Metal chelators
Inhibitor
AChE
acetylcholinesterase
AChEIs
acetylcholinesterase inhibitors
Aβ
β-amyloid
AD
Alzheimer's disease
PAS
peripheral anionic sites
BACE-1
β-secretase
MTDLs
multi-target-directed ligands
PDB
Protein Data Bank
TLC
thin layer chromatography
Design, synthesis and pharmacological evaluation of chalcone derivatives as acetylcholinesterase inhibitors
期刊论文
Bioorganic and Medicinal Chemistry, 2014, 卷号: 22, 期号: 21, 页码: 6124-6133
作者:
Liu, Hao-ran*
;
Liu, Xian-jun
;
Fan, Hao-qun
;
Tang, Jing-jing
;
Gao, Xiao-hui
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/27
AD
Alzheimer’s disease
AChE
acetylcholinesterases
ACh
acetylcholine
BuChE
butyrylcholinesterase
PAS
peripheral anionic sites
Log P
octanol/water partition
CNS
central nervous system
BBB
blood brain barrier
Chalcone derivatives
AChE inhibitors
Log P
Molecular docking
A model study of interactions between TcAChE peripheral site segment Tyr70Val71 and Loop 1 of fasciculin 2
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2006, 卷号: 24, 期号: 2, 页码: 139-148
作者:
Wang, Jing
;
Gu, Jiande
;
Leszczynski, Jerzy
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浏览/下载:11/0
  |  
提交时间:2019/01/08
Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease
期刊论文
current pharmaceutical design, 2004
Du, DM
;
Carlier, PR
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浏览/下载:2/0
  |  
提交时间:2015/11/14
acetylcholinesterase
butyrylcholinesterase
Alzheimer&apos
inhibitor
bivalent
dimer
NOOTROPIC AGENT HUPERZINE
BETA-AMYLOID AGGREGATION
K+ CHANNEL BLOCKERS
ANTICHOLINESTERASE ACTIVITY
CLICK CHEMISTRY
HIGHLY POTENT
RECEPTOR ANTAGONISTS
TORPEDO-CALIFORNICA
NAVIGATIONAL MEMORY
POLYAMINE BACKBONE
s disease
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