CORC

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CORC

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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei
收藏  |  浏览/下载：16/0  |  提交时间：2022/12/22
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei
收藏  |  浏览/下载：22/0  |  提交时间：2021/11/04
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
收藏  |  浏览/下载：33/0  |  提交时间：2020/12/21
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 180, 页码: 16
作者:  Darbalaei, Sanaz;  Yuliantie, Elita;  Dai, Antao;  Chang, Rulue;  Zhao, Peishen
收藏  |  浏览/下载：19/0  |  提交时间：2020/12/21
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.
收藏  |  浏览/下载：87/0  |  提交时间：2020/12/24
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:  Yuliantie, Elita;  Darbalaei, Sanaz;  Dai, Antao;  Zhao, Peishen;  Yang, Dehua
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24
Activation of the GLP-1 receptor by a non-peptidic agonist 期刊论文
NATURE, 2020, 页码: 432-+
作者:  Zhao, Peishen;  Liang, Yi-Lynn;  Belousoff, Matthew J.;  Deganutti, Giuseppe;  Fletcher, Madeleine M.
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:  Lei, Saifei;  Clydesdale, Lachlan;  Dai, Antao;  Cai, Xiaoqing;  Feng, Yang
收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08

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