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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Bioimaging of glutathione variation for early diagnosis of hepatocellular carcinoma using a liver-targeting ratiometric near-infrared fluorescent probe
期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2023, 页码: 9
作者:
Han, Xiaoyue
;
Xing, Yanlong
;
Song, Xinyu
;
Dou, Kun
;
Yu, Fabiao
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  |  
浏览/下载:2/0
  |  
提交时间:2024/01/26
Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
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  |  
浏览/下载:17/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin
期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:
Zhang, Lin
;
Li, Ling
;
Wang, Xia
;
Liu, Huimin
;
Zhang, Yibin
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  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
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  |  
浏览/下载:15/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China
期刊论文
THORACIC CANCER, 2022
作者:
Xu, Chunwei
;
Si, Lu
;
Wang, Wenxian
;
Li, Ziming
;
Song, Zhengbo
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  |  
浏览/下载:36/0
  |  
提交时间:2022/12/22
fusion
precision medicine
solid tumor
targeted therapy
tyrosine receptor kinase
Targeting KRAS mutant cancers: from druggable therapy to drug resistance
期刊论文
MOLECULAR CANCER, 2022, 卷号: 21
作者:
Zhu, Chunxiao
;
Guan, Xiaoqing
;
Zhang, Xinuo
;
Luan, Xin
;
Song, Zhengbo
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  |  
浏览/下载:25/0
  |  
提交时间:2022/12/23
KRAS mutations
Druggable
Resistance
Combination therapy
Optical magnetic multimodality imaging of plectin-1-targeted imaging agent for the precise detection of orthotopic pancreatic ductal adenocarcinoma in mice
期刊论文
EBIOMEDICINE, 2022, 卷号: 80, 页码: 16
作者:
Zhang, Wenjia
;
Liang, Xiaolong
;
Zhu, Liang
;
Zhang, Xinyu
;
Jin, Zhengyu
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/09/19
Pancreatic ductal adenocarcinoma (PDAC)
Magnetic particle imaging (MPI)
Superparamagnetic iron oxide nanoparticles (SPIONs)
Fluorescence molecular imaging (FMI)
Magnetic resonance imaging (MRI)
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
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  |  
浏览/下载:76/0
  |  
提交时间:2022/02/14
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