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上海药物研究所 [13]
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期刊论文 [44]
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Superparamagnetic iron oxide nanoparticles conjugated with A beta oligomer-specific scFv antibody and class A scavenger receptor activator show therapeutic potentials for Alzheimer's Disease
期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2020, 卷号: 18, 期号: 1, 页码: 13
作者:
Liu, Xiao-ge
;
Zhang, Lun
;
Lu, Shuai
;
Liu, Dong-qun
;
Huang, Ya-ru
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/03/29
Alzheimer's disease
beta-Amyloid
Oligomer
Class A scavenger receptor
Therapy
A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 161, 页码: 35-43
作者:
Zeng, Hui
;
Li, Piaopiao
;
Zhou, Lishuang
;
Ding, Kan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/12/21
Polygala tenuifolia
Pectin
Polysaccharide
A beta(42) Alzheimer's disease
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Engineering Versatile Nanoparticles for Near-Infrared Light-Tunable Drug Release and Photothermal Degradation of Amyloid beta
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 12
作者:
Lai, Yi
;
Zhu, Yingying
;
Xu, Zhiai
;
Hu, Xianli
;
Saeed, Madiha
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Alzheimer's disease
amyloid beta
conjugated polymer
light-triggered drug release
photothermal degradation
Wolfberry extracts inhibit Aˇ1-42aggregation and rescue memory lossof AD drosophila
期刊论文
Food Science and Human Wellness, 2020, 卷号: 9, 期号: 1, 页码: 64–70
作者:
Li CH(李彩虹)
;
Yang JL(杨军丽)
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/11/16
Aˇ1−42
Antioxidant bioactivity
Anti-AD potential
Bio-metal
Drosophila
Wolfberry
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Wang, Yin-Yin
;
Tao, Hong-Rui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
selective BChE inhibitor
virtual screening
structural optimization
molecular dynamics
anti-A beta aggregation
Four new cembranoids from the Chinese soft coral Sinularia sp. and their anti-A beta aggregation activities
期刊论文
FITOTERAPIA, 2019, 卷号: 136, 页码: 6
作者:
Jiang, Cheng-Shi
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  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Soft coral
Sinularia sp.
Cembranoids
Diterpenoid
Amyloid-beta (A beta) aggregation
Molecular docking
Mulberry Diels-Alder-type adducts from Morus alba as multi-targeted agents for Alzheimer's disease
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 157, 期号: x, 页码: 82-91
作者:
Xia, Chun-Li
;
Tang, Gui-Hua
;
Guo, Yan-Qiong
;
Xu, You-Kai
;
Huang, Zhi-Shu
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/04/22
Neurodegenerative Diseases
Directed Ligands
Tree
Constituents
Design
Derivatives
Flavonoids
Decade
Target
Beta
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 183, 页码: 111737
作者:
Bai, Ping
;
Wang, Keren
;
Zhang, Pengfei
;
Shi, Jian
;
Cheng, Xinfeng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/11/04
Alzheimer's disease
Chalcone-O-Alkylamine derivatives
Multi-functional agents
Rational design
Synthesis
Precognitive effect
A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing
期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74
作者:
Zhou, Lishuang
;
Liao, Wenfeng
;
Zeng, Hui
;
Yao, Yanli
;
Chen, Xia
收藏
  |  
浏览/下载:152/0
  |  
提交时间:2019/01/08
Lycium barbarum L.
Pectin
A beta(42)
Alzheimer's disease
Amyloid precursor protein processing
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