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上海药物研究所 [28]
长春应用化学研究所 [11]
北京大学 [10]
复旦大学上海医学院 [9]
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期刊论文 [133]
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浏览/检索结果:
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A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8
作者:
Wei, Yinghui
;
Hou, Junjun
;
Lu, Pengpeng
;
Fu, Lili
;
Wang, Xiaoyan
收藏
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浏览/下载:34/0
  |  
提交时间:2022/07/26
Fluorescent probe
Near-infrared
Histone deacetylases
Idiopathic pulmonary fibrosis
Fluorescence imaging
A highly sensitive colorimetric sensing platform based on silver nanocomposites for alkaline phosphatase
期刊论文
Analytical Methods, 2022, 期号: 14, 页码: 2431-2438
作者:
Wei-Feng Wang
;
Stanislas Nsanzamahoro
;
Ying Zhang
;
Cheng-Bo Wang
;
Yan-Ping Shi
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  |  
浏览/下载:6/0
  |  
提交时间:2022/11/30
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
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  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2021, 页码: 11
作者:
Xiong, Zhaoping
;
Cheng, Ziqiang
;
Lin, Xinyuan
;
Xu, Chi
;
Liu, Xiaohong
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  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
federated learning
drug discovery
FedAMP
Non-IID data
Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
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  |  
浏览/下载:18/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
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  |  
浏览/下载:54/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Hydrogen sulfide donors: Therapeutic potential in anti-atherosclerosis
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 205
作者:
Zhang, Honghua
;
Bai, Zhongjie
;
Zhu, Longqing
;
Liang, Yan
;
Fan, Xiaohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/11/25
Hydrogen sulfide (H2S)
Synthetic organic H2S donors
Anti-Atherosclerosis
Pathogenesis
Therapeutic mechanism
Polyphotosensitizer nanogels for GSH-responsive histone deacetylase inhibitors delivery and enhanced cancer photodynamic therapy
期刊论文
Colloids and Surfaces B-Biointerfaces, 2020, 卷号: 188, 页码: 11
作者:
N. Liu,H. S. Liu,H. R. Chen,G. Wang,H. L. Teng and Y. L. Chang
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  |  
浏览/下载:2/0
  |  
提交时间:2021/07/06
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