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Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Henagliflozin, a Novel Selective Inhibitor of Sodium-Glucose Cotransporter 2, in Healthy Subjects Following Single- and Multiple-dose Administration
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 2, 页码: 396-409
作者:
Zhang, Yi-fan
;
Liu, Yan-mei
;
Yu, Chen
;
Wang, Ya-ting
;
Zhan, Yan
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/05/24
diabetes
henagliflozin
pharmacodynamics
pharmacokinetics
SGLT-2 inhibitors
Nimesulide increases the aldehyde oxidase activity of humans and rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Zhou, Lei
;
Pang, Xiao-yan
;
Hou, Xiang-yu
;
Liu, Lu
;
Guo, Zi-tao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
nimesulide
aldehyde oxidase
induction
methotrexate
hepatocytes
pharmacokinetics
drug interaction
leflunomideincreasedtherenalexposureofacyclovirbyinhibitingoat13andmrp2
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 1, 页码: 129
作者:
Liao Xiaoying
;
Deng Qiangqiang
;
Han Li
;
Wu Zhitao
;
Peng Zhaoliang
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drugdrug interaction
pharmacokinetics
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
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  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Organophosphate flame retardants and bisphenol A in children's urine in Hong Kong: has the burden been underestimated?
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 183, 页码: -
作者:
Li, Na
;
Ho, Wingkei
;
Wu, Rudolf Shiu Sun
;
Ying, Guang-Guo
;
Wang, Zijian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/09/10
Organophosphate flame retardants
Children burden
Urine
Children exposure
The lag effect of water pollution on the mortality rate for esophageal cancer in a rapidly industrialized region in China
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2019, 卷号: 26, 期号: 32, 页码: 32852-32858
作者:
Xu, Chengdong
;
Xing, Dingfan
;
Wang, Jinfeng
;
Xiao, Gexin
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  |  
浏览/下载:4/0
  |  
提交时间:2020/05/19
Esophageal cancer
Lag effect
Water pollution
Spatial analysis
Rapid industrialization
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
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  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
In situ calibration of Direct Analysis in Real Time-mass spectrometry for direct quantification: Urine excretion rate index creatinine as an example
期刊论文
TALANTA, 2019, 卷号: 201, 页码: 134-142
作者:
Zhang, Ning
;
Lu, Meiling
;
Duan, Xiaokun
;
Liu, Charles C.
;
Wang, Hailin
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/09/10
Direct analysis in real time
Direct quantification
Urinary creatinine
Stable isotope-labeled creatinine
Study of pharmacokinetics and cutaneous photosensitization of hemoporfin in healthy volunteers
期刊论文
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2019, 卷号: 26, 页码: 116-123
作者:
Xu, Junyu
;
Zhao, Xia
;
Wu, Yan
;
Tu, Ping
;
Sun, Peihong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Hemoporfin
Pharmacokinetics
Photosensitization
Mass balance
Haematoporphyrin
Estimating 24-Hour Urinary Sodium Excretion From Spot Urine Samples in Chronic Kidney Disease Patients.
期刊论文
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2019
作者:
Teng Jie
;
Zou Jianzhou
;
Ding Xiaoqiang
;
Hu Jiachang
;
Wang Yimei
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  |  
浏览/下载:34/0
  |  
提交时间:2019/12/05
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