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科研机构
海洋研究所 [9]
山东大学 [8]
复旦大学上海医学院 [7]
清华大学 [6]
武汉大学 [5]
水生生物研究所 [4]
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期刊论文 [73]
学位论文 [3]
会议论文 [2]
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Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 9
作者:
Liu Changshui
;
Zang Kun
;
Li Shihao
;
Li Fuhua
;
Ma Qingiun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/09/22
thymidylate synthase (TS)
closed conformation
deoxyuridine monophosphate (dUMP)
thymidine monophosphate (TMP)
raltitrexed
Litopenaeus vannamei
Isolation of dihydrobenzofuran derivatives from ethnomedicinal species Polygonum barbatum as anticancer compounds
期刊论文
BIOLOGICAL RESEARCH, 2019, 卷号: 52, 页码: 12
作者:
Ahmed, Ayaz
;
Raza, Yasir
;
Rashid, Umer
;
Sadiq, Abdul
;
Farooq, Umar
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/06/20
Dihydrobenzofuran
Polygonum barbatum
Ethnomedicine
Oral and lungs carcinoma
Antiangiogenesis
Anticancer
Isolation of dihydrobenzofuran derivatives from ethnomedicinal species polygonum barbatum as anticancer compounds
期刊论文
Biological research, 2019, 卷号: 52, 页码: 12
作者:
Farooq, Umar
;
Naz, Sadia
;
Shams, Afshan
;
Raza, Yasir
;
Ahmed, Ayaz
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/05/08
Dihydrobenzofuran
Polygonum barbatum
Ethnomedicine
Oral and lungs carcinoma
Antiangiogenesis
Anticancer
Polymorphism rs3819102 in thymidylate synthase and environmental factors: effects on lung cancer in Chinese population
期刊论文
CURRENT PROBLEMS IN CANCER, 2019, 卷号: 43, 期号: 1
作者:
Feng, Wei
;
Guo, Xianling
;
Huang, Haidong
;
Xu, Chang
;
Li, Yutao
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/12/05
Environmental factors
Lung cancer
rs3819102 polymorphism
Smoking
Thymidylate synthase
Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway
期刊论文
CELL COMMUNICATION AND SIGNALING, 2018, 卷号: 16
作者:
Liu, Haizhou
;
Liu, Hui
;
Zhou, Zhiyi
;
Parise, Robert A.
;
Chu, Edward
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
Colorectal cancer
Thymidylate synthase
5-fluorouracil
Traditional Chinese herbal medicine
New Insight into the Octamer of TYMS Stabilized by Intermolecular Cys43-Disulfide
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19
作者:
Xie, Dan
;
Wang, Lulu
;
Xiao, Qi
;
Wu, Xiaoyan
;
Zhang, Lin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
thymidylate synthase (TYMS)
monomer
dimer
octamer
overexpression and purification
Thymidylate synthase predicts poor response to pemetrexed chemotherapy in patients with advanced breast cancer
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 3, 页码: 3274-3280
作者:
Shan, Fei
;
Liu, Yu-Lin
;
Wang, Qiang
;
Shi, Yan-Long
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
advanced breast cancer
thymidylate synthase
pemetrexed
therapeutic
efficacy
correlation
Hypoxia induces universal but differential drug resistance and impairs anticancer mechanisms of 5-fluorouracil in hepatoma cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1642-1654
作者:
Li, Jing-qiu
;
Wu, Xian
;
Gan, Lu
;
Yang, Xiang-liang
;
Miao, Ze-hong
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
hepatocellular carcinoma
hypoxia
5-fluorouracil
sorafenib
drug resistance
Deletion of sigb causes increased sensitivity to para-aminosalicylic acid and sulfamethoxazole in mycobacterium tuberculosis
期刊论文
Antimicrobial agents and chemotherapy, 2017, 卷号: 61, 期号: 10, 页码: 12
作者:
Yang, Shan-Shan
;
Hu, Yang-Bo
;
Wang, Xu-De
;
Gao, Yun-Rong
;
Li, Kun
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/05/08
Mycobacterium tuberculosis
Pabb
Para-aminobenzoic acid
Para-aminosalicylic acid
Sigb
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
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