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上海药物研究所 [19]
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Plexin D1 mediates disturbed flow-induced M1 macrophage polarization in atherosclerosis
期刊论文
HELIYON, 2023, 卷号: 9, 期号: 6, 页码: 15
作者:
Zhang, Suhui
;
Zhang, Yingqian
;
Zhang, Peng
;
Wei, Zechen
;
Ma, Mingrui
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/17
Plexin D1
Macrophage polarization
Disturbed flow
Bifurcation lesions
Atherosclerosis
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
Guaianolides from Artemisia codonocephala suppress interleukine-1 beta secretion in macrophages
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 192, 页码: 10
作者:
Wang, Qiaoqiao
;
Zhang, Tian
;
Ke, Chang-Qiang
;
Tang, Chunping
;
Yao, Sheng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
Artemisia codonocephala
Asteraceae
Guaianolides
Anti-inflammation
IL-1 beta
NLRP3
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Chen, Cheng
;
Ren, Yong-mei
;
Zhu, Jian-zhong
;
Chen, Jia-li
;
Feng, Zhe-ling
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/01/04
Ainsliadimer C
interleukin-1 beta
macrophages
NLRP3 inflammasome
Sirtuin 1
adipose tissue inflammation
obesity
metabolic disorders
EX-527
dexamethasone
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Biscaesalmins A and B from Caesalpinia minax, highly oxidized dimeric cassane diterpenoids as interleukin-1 beta inhibitors
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 4, 页码: 1475-1479
作者:
Xu, Yunshao
;
Zhang, Tian
;
Feng, Lu
;
Feng, Zheling
;
Zhang, Qingwen
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/08/17
Caesalpinia minax
IL-1 beta
Dimeric cassane diterpenoids
NLRP3
TD-DFT
In Vitro Immunotoxicity of Organophosphate Flame Retardants in Human THP-1-Derived Macrophages
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 卷号: 54, 期号: 14, 页码: 8900-8908
作者:
Li, Xinyan
;
Li, Na
;
Rao, Kaifeng
;
Huang, Qinghui
;
Ma, Mei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/09/15
MicroRNA-21 attenuates BDE-209-induced lipid accumulation in THP-1 macrophages by downregulating Toll-like receptor 4 expression
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2019, 卷号: 129, 页码: 71-77
作者:
Zhi, Hui
;
Yuan, Na
;
Wu, Jiang-Ping
;
Lu, Lin-Ming
;
Chen, Xiao-Yun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/04/27
Borrelia burgdorferi basic membrane protein A initiates proinflammatory chemokine storm in THP 1-derived macrophages via the receptors TLR1 and TLR2
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 115
作者:
Zhao, Hua
;
Dai, Xiting
;
Han, Xinlin
;
Liu, Aihua
;
Bao, Fukai
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/04
Borrelia burgdorferi
Lyme disease
Lyme arthritis
THP-1 cell
Macrophage
Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-alpha Identifies Antiviral Proteins Enriched in Exosomes
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3
作者:
Yao, Zhenlan
;
Jia, Xiaofang
;
Megger, Dominik A.
;
Chen, Jieliang
;
Liu, Yuyi
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/05
IFN-alpha
exosomes
macrophages
label-free quantification
ISGs
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