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Additive effects of variants of unknown significance in replication repair-associated DNA polymerase genes on mutational burden and prognosis across diverse cancers 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:  Ying, Jieer;  Yang, Lin;  Yin, Jiani C.;  Xia, Guojie;  Xing, Minyan
收藏  |  浏览/下载:29/0  |  提交时间:2021/11/15
Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation 期刊论文
CELL REPORTS, 2018, 卷号: 25, 期号: 4, 页码: 884-+
作者:  Liu, Liu Daisy;  Huang, Min;  Dai, Pengfei;  Liu, Tingting;  Fan, Shuangshuang
收藏  |  浏览/下载:78/0  |  提交时间:2019/04/28
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes 期刊论文
CELL RESEARCH, 2018, 卷号: 28, 期号: 10, 页码: 981-995
作者:  Chen, Juan;  Cai, Zhaokui;  Yu, Xiaohua;  Cao, Changchang;  Hu, Xihao
收藏  |  浏览/下载:110/0  |  提交时间:2019/04/28
Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation 期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2016, 卷号: 13, 期号: 3, 页码: 379-390
作者:  Wu, Yanwei;  He, Shijun;  Bai, Bingxin;  Zhang, Luyao;  Xue, Lu
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Epigenetic dynamics in immunity and autoimmunity 期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 65-74
作者:  Zhao, Ming;  Wang, Zijun;  Yung, Susan;  Lu, Qianjin*
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/03
Epigenetic dynamics  Immune system  Autoimmune diseases  DNA methylation  Histone modifications  DNMT  DNA methyltransferase  TET  ten-eleven translocation  AID/AICDA  activation-induced cytidine deaminase  APOBEC  Apolipoprotein B mRNA editing enzyme  BER  base excision repair  MBD4  methyl-CpG binding domain protein 4  HATs  histone acetyltransferases  HDAC  histone deacetylase  HMT  histone methyltransferase  5mC  5-methylcytosine  5hmC  5-hydroxymethylcytosine  GC  germinal center  DC  dendritic cell  SHM  somatic hypermutation  CSR  class switch recombination  Blimp-1  B lymphocyte-induced maturation protein-1  Treg  regulatory T  NFAT  nuclear factor of activated T-cells  TSDR  Treg-specific demethylated region  PDCD1  programmed cell death 1  Prf1  Perforin  Gzmb  Granzyme B  CTL  cytotoxic T cell  EBF1  early B cell factor1  Pax5  Paired box protein  TSA  Trichostatin A  SLE  systemic lupus erythematosus  RA  rheumatoid arthritis  MS  multiple sclerosis  T1D  type 1 diabetes mellitus  ERK  extracellular regulated protein kinases  PBMC  peripheral blood mononuclear cell  PAD2  peptidylarginine deiminase 2  IGFBP-1  insulin-like growth factor-binding protein 1  LPS  lipopolysaccharide  
Expansion and Somatic Hypermutation of B-cell Clones in Rejected Human Kidney Grafts 期刊论文
TRANSPLANTATION, 2014, 卷号: 98, 期号: 7
作者:  Ferdman, Jack;  Porcheray, Fabrice;  Gao, Baoshan;  Moore, Carolina;  DeVito, Julie
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
Sequence variability of fibrinogen-related proteins (FREPs) in Crassostrea gigas 期刊论文
CHINESE SCIENCE BULLETIN, 2012, 卷号: 57, 期号: 25, 页码: 3312-3319
作者:  Zhang LinLin;  Li Li;  Zhang GuoFan
收藏  |  浏览/下载:20/0  |  提交时间:2013/09/24
Affinity maturation of anti-TNF-alpha scFv with somatic hypermutation in non-B cells 期刊论文
PROTEIN & CELL, 2012, 卷号: 3, 期号: 6, 页码: 460-469
Chen, Shaopeng; Qiu, Junkang; Chen, Chuan; liu, chunchun; 刘春春; Liu, Yuheng; An, Lili; jia, junying; 贾俊英; Tang, Jie; 唐捷; Wu, Lijun; Hang, Haiying; 杭海英
收藏  |  浏览/下载:37/0  |  提交时间:2013/12/24
R-loop-mediated genomic instability is caused by impairment of replication fork progression 期刊论文
genes development, 2011
Gan, Wenjian; Guan, Zhishuang; Liu, Jie; Gui, Ting; Shen, Keng; Manley, James L.; Li, Xialu
收藏  |  浏览/下载:5/0  |  提交时间:2015/11/13
Characterization of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in Shanghai, China: Molecular and cytogenetic characteristics, IgV gene restriction and hypermutation patterns 期刊论文
LEUKEMIA RESEARCH, 2009, 卷号: 33, 期号: 12
作者:  Irons, Richard D.;  Le, Anh;  Bao, Liming;  Zhu, Xiongzeng;  Ryder, John
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/19


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