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Integrated application of transcriptomics and metabolomics provides insights into acute hepatopancreatic necrosis disease resistance of Pacific white shrimp Litopenaeus vannamei
期刊论文
MSYSTEMS, 2023, 页码: 20
作者:
Sun, Mingzhe
;
Yu, Yang
;
Li, Shihao
;
Liu, Yuan
;
Zhang, Xiaojun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/13
Litopenaeus vannamei
acute hepatopancreatic necrosis disease
disease resistance
transcriptome
metabolome
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)
期刊论文
PHARMACEUTICS, 2022, 卷号: 14
作者:
Liang, Huamin
;
Zou, Fengming
;
Fu, Liyi
;
Liu, Qingwang
;
Wang, Beilei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
drug nanocrystal
stabilizer
micelle
BCR-ABL
chronic myeloid leukemia (CML)
Frequency and Spectrum of Mutations Induced by Gamma Rays Revealed by Phenotype Screening and Whole-Genome Re-Sequencing in Arabidopsis thaliana
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 2, 页码: 22
作者:
Du, Yan
;
Feng, Zhuo
;
Wang, Jie
;
Jin, Wenjie
;
Wang, Zhuanzi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/04/11
gamma rays
mutation
phenotype screening
whole-genome re-sequencing
Arabidopsis thaliana
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
Influence of sulfamethazine (SMT) on the adsorption of antimony by the black soil: Implication for the complexation between SMT and antimony
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 760, 页码: 12
作者:
Fan, Yurui
;
Zheng, Chunli
;
Lin, Zishen
;
Huo, Aidi
;
Li, Risheng
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/05/08
Antimony(V)
Sulfamethazine
Adsorption
Complexation
Soil
Synthetic Studies toward DNA-Encoded Heterocycles Based on the On-DNA Formation of alpha,beta-Unsaturated Ketones
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 3, 页码: 908-913
作者:
Liu, Sixiu
;
Qi, Jingjing
;
Lu, Weiwei
;
Wang, Xuan
;
Lu, Xiaojie
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/05/24
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
期刊论文
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:
Zhao, Jie
;
Xie, Cen
;
Wang, Kanglong
;
Takahashi, Shogo
;
Krausz, Kristopher W.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/21
Triptolide
Transcriptomics
Metabolomics
Apoptosis
Acylcarnitine
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant
期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:
Hu, Xianglong
;
Xun, Qiuju
;
Zhang, Tao
;
Zhu, Su-Jie
;
Li, Qian
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
EGFR(C797S) mutant
SARs
2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine
Clinical resistance
Fourth-generation inhibitors
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