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Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii
期刊论文
FITOTERAPIA, 2021, 卷号: 153, 页码: 5
作者:
Zong, Jian-Fa
;
Zhang, Meng-Meng
;
Zhou, Yu-Bo
;
Li, Jia
;
Hou, Ai-Jun
收藏
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浏览/下载:64/0
  |  
提交时间:2021/11/04
Hypericum forrestii (Chittenden) N Robson
Clusiaceae
Acylphloroglucinol meroterpenoid
Hyperiforins A-C
Protein tyrosine phosphatase 1B
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
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  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
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  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes
期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:
Luo, Jiao
;
Hou, Yufei
;
Xie, Mengyue
;
Ma, Wanli
;
Shi, Dayong
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  |  
浏览/下载:31/0
  |  
提交时间:2020/09/25
CYC31
PTP1B inhibitor
insulin resistance
fatty acid oxidization
Hyperprins A and B, Two Complex Meroterpenoids from Hypericum przewalskii
期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 7, 页码: 2797-2800
作者:
Zong, Jian-Fa
;
Hu, Zhu
;
Shao, Ying-Ying
;
Shi, Qing
;
Zhang, Meng-Meng
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  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Spirobiflavonoid stereoisomers from the endangered conifer Glyptostrobus pensilis and their protein tyrosine phosphatase 1B inhibitory activity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 4
作者:
Xiong, Juan
;
Hu, Chang-Ling
;
Wang, Pei-Pei
;
Gao, Ding-Ding
;
Huang, Fang
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  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Glyptostrobus pensilis
Cupressaceae
Endangered conifer
Spirobiflavonoids
PTP1B inhibition
Chemical and biological comparison of different parts of Paeonia suffruticosa (Mudan) based on LCMS-IT-TOF and multi-evaluation in vitro
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2020, 卷号: 144, 页码: 9
作者:
Pan, Yang
;
Gao, Zhen
;
Huang, Xiao-Yan
;
Chen, Ji-Jun
;
Geng, Chang-An
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/03/24
Paeonia suffruticosa
Chemical profiles
LCMS-IT-TOF analyses
Biological comparison
Neurotransmitter receptors
Enzyme inhibition
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats
期刊论文
RSC ADVANCES, 2020, 卷号: 10, 期号: 6, 页码: 3429-3437
作者:
Guo, Shuju
;
Wang, Lijun
;
Chen, Dong
;
Jiang, Bo
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/03/20
The chemical components ofCoreopsis tinctoriaNutt. and their antioxidant, antidiabetic and antibacterial activities
期刊论文
NATURAL PRODUCT RESEARCH, 2020, 卷号: 34, 期号: 12, 页码: 1772-1776
作者:
Begmatov, N (Begmatov, Nurmirza)[ 1,2,4 ]
;
Li, J (Li, Jun)[ 1,2 ]
;
Bobakulov, K (Bobakulov, Khayrulla)[ 3 ]
;
Numonov, S (Numonov, Sodik)[ 1,2 ]
;
Aisa, HA (Aisa, Haji Akber)[ 1,2 ]
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/06/29
Coreopsis tinctoriaNutt
chemical components
antioxidant
antidiabetic
antibacterial
PTP1B enzymatic inhibition
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:
Xu, Qi
;
Wu, Ning
;
Li, Xiangqian
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/20
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