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CORC

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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:  Zhang, Mengqi;  Liu, Haiming;  He, Jiajin;  Gui, Yuzhou;  Qian, Hongjie
收藏  |  浏览/下载：31/0  |  提交时间：2020/12/24
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Tian, Qian-qian;  Zhu, Yun-ting;  Diao, Xing-xing;  Zhang, Xiang-lei;  Xu, Ye-chun
收藏  |  浏览/下载：70/0  |  提交时间：2020/12/24
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：57/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
PHOSPHODIESTERASE INHIBITOR TYPE 5 (PDE 5), AND PREPARATION METHOD AND APPLICATION THEREOF 专利
申请日期: 2019-01-03, 公开日期: 2019-01-03
作者:  Lou HX(娄红祥);  Zheng HB(郑泓波);  Sun B(孙斌);  Li L(李琳);  Gao Y(高云)
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04
Alpha-blockers with or without phosphodiesterase type 5 inhibitor for treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia: a systematic review and meta-analysis 期刊论文
2019, 卷号: 37, 期号: 1, 页码: 143-153
作者:  Zhang, Jianzhong;  Li, Xiao;  Yang, Bin;  Wu, Cheng;  Fan, Yanghua
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/03
Two Birds with One Stone: Regular Use of PDE5 Inhibitors for Treating Male Patients with Erectile Dysfunction and Cardiovascular Diseases 期刊论文
2019, 卷号: 33, 期号: 1, 页码: 119-128
作者:  Cai, Zhonglin;  Zhang, Jianzhong;  Li, Hongjun
收藏  |  浏览/下载：4/0  |  提交时间：2020/01/03
吸入型药物重新用于哮喘治疗 科技动态
2018
作者:  yaoxn@llas.ac.cn
收藏  |  浏览/下载：14/0  |  提交时间：2018/07/05
Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that act on downstream effectors of G-protein-coupled receptors 期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 2, 页码: 333-339
作者:  Liang, Xiao;  Chen, Yu-Ru;  Gao, Wei;  Guo, Xing-Pan;  Ding, De-Wen
收藏  |  浏览/下载：9/0  |  提交时间：2019/08/19

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