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科研机构
水生生物研究所 [2]
中国科学院大学 [2]
海洋研究所 [2]
烟台海岸带研究所 [2]
西安交通大学 [1]
上海药物研究所 [1]
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期刊论文 [18]
学位论文 [1]
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2021 [1]
2019 [1]
2018 [2]
2016 [3]
2015 [2]
2014 [3]
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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
EsTrx-2, the mitochondrial thioredoxin from Antarctic microcrustacean (Euphausia superba): Cloning and functional characterization
期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2019, 卷号: 231, 页码: 52-58
作者:
Li, Fengmei[1]
;
Liang, Yanjiao[2]
;
Cai, Jinling[3]
;
Shi, Yanjing[4]
;
Ma, Liyan[5]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/02
Microcrustacean
Euphausia superba
Mitochondrial thioredoxin 2
Redox activity
Oxidative stress
Loss of thioredoxin 2 alters mitochondrial respiratory function and induces cardiomyocyte hypertrophy
期刊论文
EXPERIMENTAL CELL RESEARCH, 2018, 卷号: 372, 期号: 1
作者:
Hu, Chunyan
;
Zhang, Hao
;
Qiao, Zhengdong
;
Wang, Yueqian
;
Zhang, Peng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
Thioredoxin 2
Cardiomyocyte
Mitochondria
AMPK
Hypertrophy
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:
Han, Yachun
;
Xu, Xiaoxuan
;
Tang, Chengyuan
;
Gao, Peng
;
Chen, Xianghui
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/03
ALT
alanine aminotransferase
AST
aspartate aminotransferase
BUN
blood urea nitrogen
BW
body weight
BG
blood glucose
DCFDA
dichlorodihydrofluorescein diacetate
DN
diabetic nephropathy
ECL
enhanced chemiluminescence
EM
electron microscopy
EMT
epithelial–mesenchymal transition
HbA1C
hemoglobin A1c
HE
hematoxylin-eosin
IF
immunofluorescence
IHC
immunohistochemistry
KW
kidney weight
LDL
low-density lipoprotein
MDA
malondialdehyde
MFI
median fluorescence intensity
MMP
mitochondrial transmembrane potential
MMT
methyl methane-thiosulphonate
MPTP
mitochondrial permeability transition pore
MSU
monosodium urate
MtROS
mitochondria reactive oxygen species
PAS
periodic acid-Schiff
Scr
serum creatinine
TC
total cholesterol
TG
triglyceride
TBARS
thiobarbituric acid reactive substances
TPP
triphenylphosphonium
TRX
thioredoxin
TXNIP
thioredoxin-interacting protein
TUNEL
terminal deoxynucleotidyl transferase dUTP nick end-labeling
8-OHdG
8-oxo-deoxyguanosine
UA
uric acid
Diabetic nephropathy
Mitochondria
Reactive oxygen species (ROS)
TRX/TXNIP
NLRP3 inflammasome
MitoQ
里氏木霉纤维素酶成熟分泌过程限制因子的研究
学位论文
博士, 北京: 中国科学院研究生院, 2016
作者:
王国坤
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2017/09/08
里氏木霉
纤维素酶
未折叠蛋白响应
二硫键异构酶
硫氧还蛋白
Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 31
作者:
Shen, Kaikai
;
Lu, Fangfang
;
Xie, Jianling
;
Wu, Minfeng
;
Cai, Bo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
breast cancer
cambogin
reactive oxygen species
NADPH oxidase 1
thioredoxin-1/ASK1 complex
TrxR2 deficiencies promote chondrogenic differentiation and induce apoptosis of chondrocytes through mitochondrial reactive oxygen species
期刊论文
EXPERIMENTAL CELL RESEARCH, 2016, 卷号: 344, 期号: [db:dc_citation_issue], 页码: 67-75
作者:
Yan, Jidong
;
Xu, Jing
;
Fei, Yao
;
Jiang, Congshan
;
Zhu, Wenhua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
Mitochondria
Thioredoxin reductase 2
Reactive oxygen species
Chondrocyte differentiation
Selenite-Induced Toxicity in Cancer Cells Is Mediated by Metabolic Generation of Endogenous Selenium Nanoparticles
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2015, 卷号: 14, 期号: 2, 页码: 1127—1136
作者:
Bao, P
;
Chen, Z
;
Tai, RZ
;
Shen, HM
;
Martin, FL
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/12/09
SODIUM-SELENITE
MITOCHONDRIAL DAMAGE
OXIDATIVE STRESS
HEPG2 CELLS
APOPTOSIS
CYTOTOXICITY
THIOREDOXIN
ATTENUATION
GLYCOLYSIS
EXPRESSION
Thioredoxin-2 Inhibits Mitochondrial Reactive Oxygen Species Generation and Apoptosis Stress Kinase-1 Activity to Maintain Cardiac Function
期刊论文
CIRCULATION, 2015, 卷号: 131, 页码: 1082-+
作者:
Huang, Qunhua[1]
;
Zhou, Huanjiao Jenny[1,2]
;
Zhang, Haifeng[1]
;
Huang, Yan[1]
;
Hinojosa-Kirschenbaum, Ford[3]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/25
cardiomyopathy, dilated
heart failure
ASK1/MAPKKK5
mitochondria
thioredoxins
CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2014, 卷号: 1842, 期号: 7, 页码: 1121-1129
作者:
Li, Chang
;
Wang, Lei
;
Zhang, Jing
;
Huang, Mi
;
Wong, Fulton
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2014/08/13
CERKL
TRX2
Oxidative stress
Retina
Apoptosis
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