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西北高原生物研究所 [19]
上海药物研究所 [16]
过程工程研究所 [13]
海洋研究所 [10]
北京大学 [8]
山东大学 [8]
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期刊论文 [137]
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Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
收藏
  |  
浏览/下载:212/0
  |  
提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis
Improvement of d-lactic acid productivity by introducing Escherichia coli acetyl-CoA synthesis pathway in engineered Saccharomyces cerevisiae
期刊论文
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2021, 页码: 11
作者:
Zhong, Wei
;
Yang, Maohua
;
Hao, Xuemi
;
Sharshar, Moustafa M.
;
Wang, Qinhong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/31
d‐
lactic acid
acetylating acetaldehyde dehydrogenase
acetyl‐
CoA
metabolic engineering
Saccharomyces cerevisiae
Detrimental impact of hypoxia on the mortality, growth, reproduction, and enzyme activities of planktonic mysid Neomysis awatschensis
期刊论文
AQUATIC ECOLOGY, 2021, 页码: 11
作者:
Wang, Qiao-ning
;
Li, Xiao-dong
;
Yan, Tian
;
Song, Jing-jing
;
Yu, Ren-cheng
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/06/24
Hypoxia
Lethal effect
Neomysis awatschensis
Long-term impact
Enzyme activity
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Improvement of D-lactic acid production at low pH through expressing acid-resistant gene IoGAS1 in engineered Saccharomyces cerevisiae
期刊论文
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2020, 页码: 11
作者:
Zhong, Wei
;
Yang, Maohua
;
Hao, Xuemi
;
Sharshar, Moustafa Mohamed
;
Wang, Qinhong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/03/29
d‐
lactic acid
acid‐
resistant gene
IoGAS1
rational metabolic engineering
Saccharomyces cerevisiae
Metabolic engineering of Cupriavidus necator H16 for improved chemoautotrophic growth and PHB production under oxygen-limiting conditions
期刊论文
METABOLIC ENGINEERING, 2020, 卷号: 61, 页码: 11-23
作者:
Tang, Ruohao
;
Weng, Caihong
;
Peng, Xiaowei
;
Han, Yejun
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/03/29
Cupriavidus necator H16
Carbon dioxide
Oxygen-limiting conditions
Transcription
Metabolic engineering
Ployhydroxybutyrate
Liver toxicity of macrolide antibiotics in zebrafish
期刊论文
TOXICOLOGY, 2020, 卷号: 441, 页码: 12
作者:
Zhang, Miao-qing
;
Chen, Bo
;
Zhang, Jing-pu
;
Chen, Ning
;
Liu, Chun-zhao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/09/22
Liver toxicity
Macrolides
ADMET
RNA-seq analysis
Differentially expressed genes
c-Fos
The supplement of vitamin C facilitates L-lactic acid biosynthesis in Lactobacillus thermophilus A69 from sweet sorghum juice coupled with soybean hydrolysate as feedstocks
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2020, 卷号: 146, 页码: 7
作者:
Tian, Xuejiao
;
Hu, Wei
;
Chen, Jihong
;
Zhang, Wei
;
Li, Wenjian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/18
Vitamin C
L-lactic acid
Sweet sorghum juice
Antioxidant capacity
Fermentation efficiency
Alpha-hydroxybutyrate dehydrogenase as a biomarker for predicting systemic lupus erythematosus with liver injury
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2019, 卷号: 77
作者:
Yu, Haitao
;
Han, Hengtong
;
Li, Jiajia
;
Li, Danyang
;
Jiang, Lili
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/03/01
Systemic lupus erythematosus
Liver injury
Association rules mining
Biomarker
Alpha-hydroxybutyrate dehydrogenase
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