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上海药物研究所 [8]
中国医学科学院 北京... [3]
兰州大学 [1]
高能物理研究所 [1]
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期刊论文 [13]
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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Nitidine chloride exerts anti-inflammatory action by targeting Topoisomerase I and enhancing IL-10 production
期刊论文
2019, 卷号: 148, 页码: 104368
作者:
Yang Niao
;
Yue Rongcai
;
Ma Jinzhu
;
Li Wencai
;
Zhao Zeng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/01/03
Chelerythrine Chloride (PubChem CID: 72311)
DNA topoisomerase I inhibitor
Endotoxemia
Interleukin-10
Irinotecan hydrochloride (PubChem CID: 74990)
LY294002 (PubChem CID: 3973)
Lipopolysaccharide
MK-2206 (PubChem CID: 46930998)
Nitidine Chloride (PubChem CID: 25659)
Phosphatidylinositol 3-kinase/Akt pathway
SN-38 (PubChem CID: 104842)
Sanguinarine chloride (PubChem CID: 68635)
Topotecan hydrochloride (PubChem CID: 60699)
A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection
期刊论文
2019, 卷号: 170, 页码: 112-123
作者:
Zhuang, Quankun
;
Liu, Xuemei
;
Sun, Zhuo
;
Wang, Hongyun
;
Jiang, Ji
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
Free irinotecan
SN-38
SN-38G
UPLC-MS/MS
SPE
Irinotecan hydrochloride liposome injection
Lal test and rpt for endotoxin detection of cpt-11/dspe-mpeg(2000) nanoformulation: what if traditional methods are not applicable?
期刊论文
Asian journal of pharmaceutical sciences, 2018, 卷号: 13, 期号: 3, 页码: 289-296
作者:
Jin, Yanan
;
Jia, Juanjuan
;
Li, Chan
;
Xue, Jianqi
;
Sun, Jiabei
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/04/23
Irinotecan hydrochloride
Endotoxin detection
Micelle
Dspe-mpeg(2000)
Limulus amebocyte lysate assay
Rabbit pyrogen test
Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample pr
期刊论文
2017, 卷号: 7, 期号: 69, 页码: 43621-43635
作者:
Guan, Huanyu
;
Wang, Xiaoming
;
Wang, Shiping
;
He, Yang
;
Yue, Jiajing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Effect of hesperidin on the pharmacokinetics of CPT-11 and its active metabolite SN-38 by regulating hepatic Mrp2 in rats
期刊论文
BIOPHARMACEUTICS & DRUG DISPOSITION, 2016, 卷号: 37, 期号: 7, 页码: 421-432
作者:
Wang, XD
;
Rao, Z
;
Qin, HY
;
Zhang, GQ
;
Ma, YR
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/05/08
irinotecan hydrochloride
SN-38
Mrp2
hesperidin
pharmacokinetics
Preparation and in vitro Antitumor Activity of Irinotecan Hydrochloride Liposomes
期刊论文
Chinese Journal of Pharmaceuticals, 2013, 卷号: 44, 期号: 6, 页码: 576-580
作者:
Fan Jitao
;
Cao Haiqiang
;
Liu Zeying
;
Li Yaping
;
Chen Lingli
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
irinotecan hydrochloride
liposome
preparation
ammonium sulfate gradient method
in vitro antitumor activity
RP-HPLC determination of irinotecan hydrochloride(CPT-11) and its related substances
期刊论文
Chinese Journal of Pharmaceutical Analysis, 2013, 卷号: 33, 期号: 3, 页码: 439-442
作者:
Qiao Shanbao
;
Ji Min
;
Xiang Lili
;
Chen Dongying
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
HPLC
ion - pair
irinotecan hydrochloride (CPT - 11)
impurity analysis
forced degradation
quality control
camptothecin derivatives
Preparation and characterization of irinotecan hydrochloride loaded PEO-PPO-PEO micelles and its mechanism of decreasing drug intestinal toxicity
期刊论文
Yao xue xue bao = Acta pharmaceutica Sinica, 2012, 卷号: 47, 期号: 11, 页码: 1534-40
作者:
Zhang, Xin-Xin
;
Guo, Shi-Yan
;
Li, Fei-Fei
;
Gan, Yong
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
Preparation and characterization of irinotecan hydrochloride loaded PEO-PPO-PEO micelles and its mechanism of decreasing drug intestinal toxicity
期刊论文
Acta Pharmaceutica Sinica, 2012, 卷号: 47, 期号: 11, 页码: 1534-1540
作者:
Zhang Xinxin
;
Guo Shiyan
;
Li Feifei
;
Gan Yong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
PEO-PPO-PEO
irinotecan
micelle
breast cancer resistance protein
PEO-PPO-PEO
diarrhea
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