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Structural insights into catalytic mechanism and product delivery of cyanobacterial acyl-acyl carrier protein reductase
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 11
作者:
Gao, Yu
;
Zhang, Hongmei
;
Fan, Minrui
;
Jia, Chenjun
;
Shi, Lifang
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae
期刊论文
Microbial Cell Factories, 2017, 卷号: 16, 期号: 1
作者:
Zhou,Yongjin J.
;
Nielsen,Jens
;
Teixeira,Paulo Gon?alves
;
Ferreira,Raphael
;
Siewers,Verena
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/06/20
Fatty alcohols
Fatty acid activation
FAA1
Dynamic control
Yeast
Metabolic engineering
The Acyl Desaturase CER17 Is Involved in Producing Wax Unsaturated Primary Alcohols and Cutin Monomers
期刊论文
PLANT PHYSIOLOGY, 2017, 卷号: 173, 期号: 2, 页码: 1109-1124
作者:
Yang, Xianpeng
;
Zhao, Huayan
;
Kosma, Dylan K.
;
Tomasi, Pernell
;
Dyer, John M.
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2017/12/31
High production of fatty alcohols in Escherichia coli with fatty acid starvation
期刊论文
MICROBIAL CELL FACTORIES, 2016, 卷号: 15
作者:
Liu, Yilan
;
Chen, Sha
;
Chen, Jinjin
;
Zhou, Jiemin
;
Wang, Yanyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/03/21
Escherichia coli
Fatty alcohols
Acyl-ACP thioesterases
Fatty acid starvation
High production of fatty alcohols in Escherichia coli with fatty acid starvation
期刊论文
MICROBIAL CELL FACTORIES, 2016, 卷号: 15, 期号: JUL, 页码: 129
作者:
Liu, Yilan
;
Chen, Sha
;
Chen, Jinjin
;
Zhou, Jiemin
;
Wang, Yanyan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2016/11/21
Escherichia coli
Fatty alcohols
Acyl-ACP thioesterases
Fatty acid starvation
Improved production of fatty alcohols in cyanobacteria by metabolic engineering
期刊论文
BIOTECHNOLOGY FOR BIOFUELS, 2014, 卷号: 7, 期号: 1, 页码: 1
作者:
Yao, Lun
;
Qi, Fengxia
;
Tan, Xiaoming
;
Lu, Xuefeng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/02
Fatty alcohol
Cyanobacteria
Fatty acyl-CoA reductase
Marinobacter aquaeolei VT8
Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice
期刊论文
Journal of Hepatology, 2014, 卷号: 60, 期号: 5, 页码: 1046-1054
作者:
Zhu, Li-Hua
;
Wang, Aibing
;
Luo, Pengcheng
;
Wang, Xinan
;
Jiang, Ding-Sheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
IR
insulin resistance
WT
wild type
KO
knockout
TG
transgenic
NTG
non-transgenic
NC
normal chow
HFD
high-fat diet
PPARα
peroxisome proliferator-activated receptor alpha
ECM
extracellular matrix
NL
normal liver
NAFLD
non-alcoholic fatty liver disease
H&E
hematoxylin and eosin
ALT
alanine transaminase
AST
aspartate transaminase
ALP
alkaline phosphatase
HMGCR
3-hydroxy-3-methyl-glutaryl-CoA reductase
LDL
low density lipoprotein
HDL
high density lipoprotein
LDLR
low-density lipoprotein receptor
GPAT
glycerol-3-phosphate acyltransferase
DGAT
diglyceride acyltransferase
FFA
free fatty acid
SREBP1c
sterol response element binding protein 1c
ACC
acetyl-CoA carboxylase
FAS
fatty acid synthase
SCD
stearoyl-CoA desaturase
LXR-α
liver X receptor-α
ARG-1
arginase-1
ABCA
ATP-binding cassette transporter A
ABCG
ATP-binding cassette transporter G
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
AMPK
AMP-activated protein kinase
IL
interleukin
TNF-α
tumor necrosis factor alpha
MCP-1
monocyte chemoattractant protein 1
MRC1
mannose receptor, C type 1
MGL
macrophage galactose-type C-type lectin
JNK
Jun N-terminal kinase
FBG
fasting glucose
HOMA-IR
homeostasis model assessment of insulin resistance
GTT
glucose tolerance test
ITT
intraperitoneal insulin tolerance test
Fins
fasting insulin
shRNA
short hairpin RNA
GFP
green fluorescent protein
IRS
insulin receptor substrate
Akt
protein kinase B
HSL
hormone sensitive lipase
ATGL
adipose triacylglycerol lipase
ACOX
acyl-coenzyme A oxidase
CPT-1α
carnitine palmitoyltransferase-1-α
LCAD
long-chain acyl-CoA dehydrogenase
MCAD
medium-chain acyl-CoA dehydrogenase
UCP
uncoupling protein
FGF21
fibroblast growth factor
PPRE
peroxisome proliferators response element
AUC
area under the curve
IKKβ
inhibitor of nuclear factor kappa B kinase beta subunit
Spondin 2
Fatty liver
Insulin resistance
PPARα
Metabolic engineering of fatty acyl-ACP reductase-dependent pathway to improve fatty alcohol production in Escherichia coli
期刊论文
METABOLIC ENGINEERING, 2014, 卷号: 22
作者:
Liu, Ran
;
Zhu, Fayin
;
Lu, Lei
;
Fu, Aisi
;
Lu, Jiankai
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Fatty alcohol
Fatty acyl-CoA/ACP reductase
in vitro reconstitution
Fatty aldehyde reductase
AdhP
Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase
期刊论文
Bmc complementary and alternative medicine, 2013, 卷号: 13, 期号: 1
作者:
Liang,Yan
;
Tian,Weixi
;
Ma,Xiaofeng
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/05/09
Fatty acid synthase
β-ketoacyl reductase
Inhibitor
Grape skin extract
Resveratrol
Obesity
3?t3-l1 preadipocytes
Construction, characterization and application of molecular tools for metabolic engineering of Synechocystis sp.
期刊论文
BIOTECHNOLOGY LETTERS, 2013, 卷号: 35, 期号: 10, 页码: 1655-1661
作者:
Qi, Fengxia
;
Yao, Lun
;
Tan, Xiaoming
;
Lu, Xuefeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2014/03/21
Fatty alcohol
Fatty acyl-CoA reductase
Promoters
Synechocystis sp PCC6803
Synthetic biology
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