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上海药物研究所 [34]
昆明植物研究所 [7]
大连理工大学 [6]
长春应用化学研究所 [6]
湖南大学 [4]
北京大学 [3]
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Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat with in Vitro Hydrolysis and Anticancer Effects
期刊论文
ACS OMEGA, 2020, 卷号: 5, 期号: 1, 页码: 350-357
作者:
Liu, Shuangxi
;
Hu, Zonglong
;
Zhang, Qiumeng
;
Zhu, Qiwen
;
Chen, Yi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus
期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 713-717
作者:
Yan, Huan
;
Qin, Xu-Jie
;
Li, Xu-Hong
;
Yu, Qian
;
Ni, Wei
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  |  
浏览/下载:65/0
  |  
提交时间:2019/04/15
Chloranthus japonicus
Lindenane sesquiterpenoid dimer
Japonicones A-C
ECD calculation
Nitidine chloride exerts anti-inflammatory action by targeting Topoisomerase I and enhancing IL-10 production
期刊论文
2019, 卷号: 148, 页码: 104368
作者:
Yang Niao
;
Yue Rongcai
;
Ma Jinzhu
;
Li Wencai
;
Zhao Zeng
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/01/03
Chelerythrine Chloride (PubChem CID: 72311)
DNA topoisomerase I inhibitor
Endotoxemia
Interleukin-10
Irinotecan hydrochloride (PubChem CID: 74990)
LY294002 (PubChem CID: 3973)
Lipopolysaccharide
MK-2206 (PubChem CID: 46930998)
Nitidine Chloride (PubChem CID: 25659)
Phosphatidylinositol 3-kinase/Akt pathway
SN-38 (PubChem CID: 104842)
Sanguinarine chloride (PubChem CID: 68635)
Topotecan hydrochloride (PubChem CID: 60699)
Eucalypglobulusals A-J, Formyl-Phloroglucinol-Terpene Meroterpenoids from Eucalyptus globulus Fruits
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 12, 页码: 2638-2646
作者:
Qin, Xu-Jie
;
Jin, Ling-Yu
;
Yu, Qian
;
Liu, Hui
;
Khan, Afsar
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/03/18
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:
Gu, Hongling
;
Li, Na
;
Dai, Jiangkun
;
Xi, Yaxi
;
Wang, Shijun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
bivalent -carbolines
antitumor
apoptosis
DNA-binding affinity
bcl-2
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
An Autoantibody Against Human DNA-Topoisomerase I Is a Novel Biomarker for Non-Small Cell Lung Cancer
期刊论文
2018, 卷号: 105, 期号: 6, 页码: 1664-1670
作者:
Wu, Wen-bin
;
Yie, Shang-mian[2]
;
Ye, Shang-rong
;
Xie, Ke
;
Zhang, Jian-bo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/06
Topoisomerase I inhibitory and photocleavage activity of non-dppz DNA "light switches\' based on ruthenium complexes containing nitro group
期刊论文
APPLIED ORGANOMETALLIC CHEMISTRY, 2018, 卷号: Vol.32 No.8
作者:
Liu, XueWen
;
Huang, Jie
;
Tang, YuXuan
;
Shen, YouMing
;
Lu, JiLin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/26
DNA "light switch\'
nitro group
non-dppz
ruthenium complex
topo I inhibition
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