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科研机构
过程工程研究所 [5]
厦门大学 [3]
湖南农业大学 [1]
上海生物化学与细胞生... [1]
中国医学科学院 北京... [1]
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期刊论文 [10]
学位论文 [1]
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2021 [2]
2020 [1]
2018 [4]
2014 [1]
2012 [1]
2005 [2]
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Virology [1]
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Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
作者:
Zhang, Yao
;
Liu, Yongdong
;
Zhang, Bingyang
;
Yin, Shuang
;
Li, Xiunan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/31
Hepatitis B core (HBc)
Uniform VLPs
Nucleic acid removal
Disassembly-purification-reassembly
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol
期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
作者:
Zhang, Yao
;
Yin, Shuang
;
Zhang, Bingyang
;
Bi, Jingxiu
;
Liu, Yongdong
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/05/06
Virus-like particle (VLP)
Hepatitis B virus core antigen (HBc)
Inclusion body
Assembly
Sodium dodecyl sulfate (SDS)
2-methyl-2, 4-pentanediol (MPD)
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
作者:
Ji, Mei
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Yu, Xiao-lin
;
Zhang, Yue
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2018/07/17
Alzheimer's Disease
Frontotemporal Dementia
Hepatitis b Core Protein
Truncated Tau
Neurofibrillary Tangles
Virus-like Particles (Vlps)
Vaccine
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
作者:
Ji, M
;
Xie, XX
;
Liu, DQ
;
Yu, XL
;
Zhang, Y
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2018/12/29
Alzheimer's Disease
Virus-like Particles
Frontotemporal Dementia
In-vivo
Hepatitis b Core Protein
Neurofibrillary Degeneration
Truncated Tau
Corticobasal Degeneration
Neurofibrillary Tangles
Structural Determinants
Virus-like Particles (Vlps)
Truncated Tau
Vaccine
Immunotherapy
Protein
Pathology
Tauopathy
Structure-Based Design of Porcine Circovirus Type 2 Chimeric VLPs (cVLPs) Displays Foreign Peptides on the Capsid Surface.
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2018, 卷号: 8, 期号: JUL, 页码: 232
作者:
Wang, Dongliang
;
Zhang, Sujiao
;
Zou, Yawen
;
Yu, Wanting
;
Jiang, Yifan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
*3D structure prediction
*bivalent or multivalent vaccines
*capsid protein
*chimeric virus-like particles (cVLPs)
*porcine circovirus type 2 (PCV2)
Inclusion of membrane-anchored LTB or flagellin protein in H5N1 virus-like particles enhances protective responses following intramuscular and oral immunization of mice
期刊论文
2018, 卷号: 36, 期号: 40, 页码: 5990-5998
作者:
Ren, Zhiguang
;
Zhao, Yongkun
;
Liu, Jing
;
Ji, Xianliang
;
Meng, Lingnan
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/01/03
H5N1 influenza
Chimeric VLPs
Vaccine
Oral immunization
Mucosally vaccinated
Immunogenicity
Chimeric Virus-Like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice through Divergent Mechanisms
期刊论文
JOURNAL OF VIROLOGY, 2014, 卷号: 88, 期号: 1, 页码: 72-81
作者:
Ye, XH
;
Ku, ZQ
;
Liu, QW
;
Wang, XL
;
Shi, JP
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/07/22
嵌合型乙肝病毒核心蛋白病毒样颗粒的原核表达及初步应用
学位论文
2012, 2012
田苗苗
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2016/02/14
基因载体
HBc VLPs
原核表达
细胞转染
Gene Vector
HBc VLPs
Prokaryotic Expression
Cell transfection
Expression and immunoactivity of chimeric particulate antigens of receptor binding site-core antigen of hepatitis B virus
期刊论文
2005
Yang, Hai-Jie
;
Chen, Min
;
Cheng, Tong
;
He, Shui-Zhen
;
Li, Shao-Wei
;
Guan, Bao-Quan
;
Zhu, Zi -Heng
;
Gu, Ying
;
Zhang, Jun
;
Xia, Ning-Shao
;
夏宁邵
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/12/12
SURFACE-ANTIGEN
C-TERMINUS
CAPSID PROTEIN
HBV INFECTION
PARTICLES
IMMUNIZATION
VACCINE
LOCALIZATION
EPITOPES
ANTIBODY
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