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CORC

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EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma 期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:  Xie, Shao;  Wei, Fan;  Sun, Yi-ming;  Gao, Ying-lei;  Pan, Lu-lu
收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
ASF/SF2调控Cyclin T1的可变剪切和转录功能的研究 学位论文
2017
作者:  周洁琼
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05
Regulation of the Alternative Splicing and Function of Cyclin T1 by the Serine-Arginine-Rich Protein ASF/SF2 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2017, 卷号: 118, 期号: 11
作者:  Zhou, Jieqiong;  Gao, Guozhen;  Hou, Panpan;  Li, Chun-Mei;  Guo, Deyin
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome 期刊论文
SCIENCE, 2016, 卷号: 351, 期号: 6275
作者:  Shi, Yuan;  Chen, Xiang;  Elsasser, Suzanne;  Stocks, Bradley B.;  Tian, Geng
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  
P-TEFb重活化的调控机制 学位论文
2015, 2013
刘江舫
收藏  |  浏览/下载：3/0  |  提交时间：2016/02/23
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation 期刊论文
http://dx.doi.org/10.1073/pnas.1318503111, 2014
Lu, Huasong; Li, Zichong; Xue, Yuhua; Schulze-Gahmen, Ursula; Johnson, Jeffrey R.; Krogan, Nevan J.; Alber, Tom; Zhou, Qiang; 薛玉花; 周强
收藏  |  浏览/下载：3/0  |  提交时间：2015/07/22
Brd4 and HEXIM1: Multiple Roles in P-TEFb Regulation and Cancer 期刊论文
http://dx.doi.org/10.1155/2014/232870, 2014
Chen, Ruichuan; Yik, Jasper H. N.; Lew, Qiao Jing; Chao, Sheng-Hao; 陈瑞川
收藏  |  浏览/下载：3/0  |  提交时间：2015/07/22
三黄方的药代动力学与调脂降糖作用研究 学位论文
2014
作者:  刘庆丰
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/19
Inhibition of HIV-1 Transcription and Replication by a Newly Identified Cyclin T1 Splice Variant 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 卷号: 288, 期号: 20
作者:  Gao, Guozhen;  Wu, Xiaoyun;  Zhou, Jieqiong;  He, Mingfeng;  He, Johnny J.
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05

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