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科研机构
西安交通大学 [7]
武汉大学 [7]
复旦大学上海医学院 [3]
山东大学 [2]
吉林大学白求恩第一医... [2]
北京大学 [1]
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期刊论文 [20]
学位论文 [3]
科研项目 [2]
会议论文 [1]
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2018 [1]
2017 [4]
2016 [2]
2015 [4]
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浏览/检索结果:
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Effects of connective tissue growth factor (CTGF/CCN2) on condylar chondrocyte proliferation, migration, maturation, differentiation and signalling pathway
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 495, 期号: 1
作者:
Li, Zubing
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
CCN2
Condylar chondrocyte
CTGF
Differentiation
PI3k/Akt
Proliferation
Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 卷号: 36
作者:
Jia, Qingan
;
Bu, Yang
;
Wang, Zhiming
;
Chen, Bendong
;
Zhang, Qiangbo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Hepatocellular carcinoma
CCN2
LRP6
Wnt
Combination therapy
Targeting of CCN2 suppresses tumor progression and improves chemo-sensitivity in urothelial bladder cancer
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 39
作者:
Wang, Xiaojing
;
Xu, Tianyuan
;
Gao, Fengbin
;
He, Hongchao
;
Zhu, Yu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
CCN2
bladder cancer
chemotherapy
mitomycin C
Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 卷号: 36
作者:
Jia, Qingan
;
Bu, Yang
;
Wang, Zhiming
;
Chen, Bendong
;
Zhang, Qiangbo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
LRP6
Hepatocellular carcinoma
Wnt
CCN2
Combination therapy
Expression of fibrosis-related molecules in the oral mucosa of six animal species: A reference for selecting animal models
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 96
作者:
Sa, Guoliang
;
Xiong, Xuepeng
;
Ren, Jiangang
;
Zhao, Yifang
;
He, Sangang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Oral submucous fibrosis
Animal model
TGF-beta
CCN2
Extracellular matrix
MicroRNA-143-3p inhibits hyperplastic scar formation by targeting connective tissue growth factor CTGF/CCN2 via the Akt/mTOR pathway
期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2016, 卷号: 416, 期号: [db:dc_citation_issue], 页码: 99-108
作者:
Mu, Shengzhi
;
Kang, Bei
;
Zeng, Weihui
;
Sun, Yaowen
;
Yang, Fan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
Akt/mTOR
Connective tissue growth factor
MicroRNA
Hypertrophic scar
Lysophosphatidic acid upregulates connective tissue growth factor expression in osteoblasts through the GPCR/PKC and PKA pathways
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2016, 卷号: 37, 期号: 2
作者:
Yu, Zi-Li
;
Li, Dian-Qi
;
Huang, Xiang-Yu
;
Xing, Xin
;
Yu, Ru-Qing
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
lysophosphatidic acid
connective tissue growth factor/CCN2
protein kinase C
protein kinase A
signaling pathway
CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 卷号: 36, 期号: [db:dc_citation_issue], 页码: 123-129
作者:
Xu, Honghai
;
Liu, Cong
;
Sun, Zhengming
;
Guo, Xiong
;
Zhang, Yuelin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
CCN5
CCN2
cell proliferation
Smad6
epidural fibrosis
fibrotic phenotype
CCN2 and CCN5 exerts opposing effect on fibroblast proliferation and transdifferentiation induced by TGF-
期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2015, 卷号: 42, 期号: [db:dc_citation_issue], 页码: 1207-1219
作者:
Xu, Honghai
;
Li, Peng
;
Liu, Mengting
;
Liu, Cong
;
Sun, Zhengming
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/02
CCN5
proliferation
CCN2
transdifferentiation
epidural scar
fibroblasts
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
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