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浏览/检索结果: 共10条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway 期刊论文 Cancer letters, 2018, 卷号: 444, 页码: 45-59 作者:  Xiao, Wenqin;  Xu, Zhijian;  Chang, Shuaikang;  Li, Bo;  Yu, Dandan 收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 Identification of recurrent USP48 and BRAF mutations in Cushing's disease 期刊论文 NATURE COMMUNICATIONS, 2018, 卷号: 9 作者:  Chen, Jianhua;  Jian, Xuemin;  Deng, Siyu;  Ma, Zengyi;  Shou, Xuefei 收藏  |  浏览/下载：117/0  |  提交时间：2019/01/08 Identification of recurrent USP48 and BRAF mutations in Cushing's disease 期刊论文 NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: 1, 页码: 3171 作者:  Chen, Jianhua;  Jian, Xuemin;  Song, Zhijian;  Li, Zhiqiang;  Zhou, Juan 收藏  |  浏览/下载：75/0  |  提交时间：2019/04/28 Human Cancer  Proopiomelanocortin Gene  Deubiquitinating Enzyme  Pituitary-adenomas  Kappa-b  Transcription  Activation  Raf  Pathways  Genome   Design and discovery of thioether and nicotinamide containing sorafenib analogues as multikinase inhibitors targeting B-Raf, B-Raf(V600E) and VEGFR-2 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 9, 页码: 2381-2391 作者:  Sun, Shaofeng;  He, Zuopeng;  Huang, Mindong;  Wang, Ningning;  He, Zongzhong 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Nicotinamide  B-Raf  VEGFR-2  Kinase inhibitor  Antitumor   AKT is critically involved in the antagonism of BRAF inhibitor sorafenib against dabrafenib in colorectal cancer cells harboring both wild-type and mutant (V600E) BRAF genes 期刊论文 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 489, 期号: 1, 页码: 14-20 作者:  Wang, Hongbin;  Quan, Haitian;  Lou, Liguang 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Antagonism  AKT  BRAF  Dabrafenib  Sorafenib   Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068 作者:  Wang, Gui-min;  Wang, Xiang;  Zhu, Jian-ming;  Guo, Bin-bin;  Yang, Zhuo 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 B-Raf(V600E) inhibitor  anticancer  vemurafenib  deazapurine  fragment reassembly  molecular docking  structure-activity relationship   Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors 期刊论文 Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068 作者:  Wang Guimin;  Wang Xiang;  Zhu Jianming;  Guo Binbin;  Yang Zhuo 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 B-Raf~(V600E) inhibitor  anticancer  vemurafenib  deazapurine  fragment reassembly  molecular docking  structure-activity relationship   The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury 期刊论文 CELL DEATH & DISEASE, 2014, 卷号: 5 作者:  Li, J-X;  Feng, J-M;  Wang, Y.;  Li, X-H;  Chen, X-X 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Combining pharmacophore, docking and substructure search approaches to identify and optimize novel B-Raf(V600E) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 17, 页码: 5428-5437 作者:  Xu, Zhijian;  Yan, Guirui;  Wang, Gaihong;  Li, Bo;  Zhu, Jianming 收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 B-Raf(V600E) inhibitors  Pharmacophore  Docking  Substructure search   Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, 卷号: 10, 期号: 36, 页码: 7402-7417 作者:  Kong, Xiangqian;  Qin, Jie;  Li, Zeng;  Vultur, Adina;  Tong, Linjiang 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08