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兰州大学 [13]
上海药物研究所 [7]
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武汉大学 [4]
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Serplulimab, a novel anti-PD-1 antibody, in patients with microsatellite instability-high solid tumours: an open-label, single-arm, multicentre, phase II trial
期刊论文
BRITISH JOURNAL OF CANCER, 2022
作者:
Qin, Shukui
;
Li, Jin
;
Zhong, Haijun
;
Jin, Chuan
;
Chen, Lili
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/22
Treatment outcomes and prognosis of immune checkpoint inhibitors therapy in patients with advanced thymic carcinoma: A multicentre retrospective study
期刊论文
EUROPEAN JOURNAL OF CANCER, 2022, 卷号: 174
作者:
Wang, Wenxian
;
Lin, Gen
;
Guan, Yelan
;
Zhang, Yuxin
;
Xu, Chunwei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
Thymic carcinoma
Immunotherapy
PD-1
Efficacy
Immune-related adverse events
A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
Occurrence and Biological Activities of Phenylpropionyl Iridoids
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 4
作者:
Cao, Jiaoxian
;
Yu, Hanchuan
;
Wu, Yingchun
;
Wang, Xinhong
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
Phenylpropionyl iridoids
neuroprotective activity
anti-inflammatory
antitumour
antimicrobial
antioxidant
Anti-inflammatory and antitumour activity of various extracts and compounds from the fruits of Piper longum L.
期刊论文
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 卷号: 71, 期号: 7
作者:
Guo, Ziyan
;
Xu, Jie
;
Xia, Jianhua
;
Wu, Zi
;
Lei, Jiachuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
active compound
anti-inflammatory
antitumour
extraction
Piper longum
Chlorambucil prodrug-participating catanionic aggregates for sustained drug release and improved antitumour activity.
期刊论文
Journal of Molecular Liquids, 2019, 卷号: Vol.274, 页码: 556-561
作者:
Jiang, Yue
;
Hu, Xu
;
Zhang, Jing
;
Jin, Guoxia
;
Luan, Yuxia
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/17
CHLORAMBUCIL
*PRODRUGS
*CHEMOTHERAPY
(Cancer)
*ANIONIC
surfactants
*ANTINEOPLASTIC
agents
Chlorambucil prodrug-participating catanionic aggregates for sustained drug release and improved antitumour activity
期刊论文
JOURNAL OF MOLECULAR LIQUIDS, 2019, 卷号: 274, 页码: 556-561
作者:
Jiang, Yue
;
Hu, Xu
;
Zhang, Jing
;
Jin, Guoxia
;
Luan, Yuxia
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Prodrug
Catanionic aggregates
Antitumour
Sustained release
Chlorambucil
Tetracenomycin X Exerts Antitumour Activity in Lung Cancer Cells through the Downregulation of Cyclin D1
期刊论文
2019, 卷号: 17, 期号: 1
作者:
Qiao, Xinran
;
Gan, Maoluo
;
Wang, Chen
;
Liu, Bin
;
Shang, Yue
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
tetracenomycin X
cell cycle arrest
cyclin D1
proteasomal degradation
p38
c-JUN
Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
Synthesis and antitumour activity of arctigenin amino acid ester derivatives against H22 hepatocellular carcinoma
期刊论文
NATURAL PRODUCT RESEARCH, 2018, 卷号: 32, 期号: 4
作者:
Cai, Enbo
;
Guo, Shijie
;
Yang, Limin
;
Han, Mei
;
Xia, Jing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Arctigenin
amino acid derivatives
antitumour activity
nitrite-clearing activity
water solubility
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