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上海药物研究所 [49]
湖南大学 [11]
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昆明植物研究所 [10]
合肥物质科学研究院 [9]
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Cyclopiumolides A and B, unusual 13-membered macrolides from the deep sea-sourced fungus Penicillium cyclopium SD-413 with antiproliferative activities
期刊论文
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:
Li, Yan-He
;
Yang, Sui-Qun
;
Li, Xiao-Ming
;
Li, Xin
;
Wang, Bin-Gui
收藏
  |  
浏览/下载:270/0
  |  
提交时间:2023/01/06
Macrolides
Penicillium cyclopium
Deep-sea sediment
Cytotoxicity
Dammarane Triterpenoids with Rare Skeletons from Gynostemma pentaphyllum and Their Cytotoxic Activities
期刊论文
Fitoterapia, 2022, 期号: 162, 页码: 105280
作者:
Jun Wang
;
Xian-Hua Meng
;
Wei-Feng Wang
;
Chun-Yan Sang
;
Thi-Kim-Quy Ha
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2022/11/30
Gynostemma pentaphyllum (Thunb.) Makino
Cucurbitaceae
Triterpenes, cytotoxic activities
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 页码: 7
作者:
Qi, Jingjing
;
Zhang, Yan
;
Liu, Qunfang
;
Liu, Hongchun
;
Fan, Yaoyue
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
Clerodendrum chinense
Natural products
Diterpenoids
Structural elucidation
Antiproliferative activities
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues
期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:
Uche, Fidelia Ijeoma
;
Guo, Xiaozhen
;
Okokon, Jude
;
Ullah, Imran
;
Horrocks, Paul
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
malaria
Plasmodium falciparum
Plasmodium berghei
bisbenzylisoquinoline alkaloids
cycleanine
metabolism
in vivo activity
antimalarial agents
drug metabolism
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin
期刊论文
STEROIDS, 2020, 卷号: 164, 页码: 11
作者:
Zhou, Yang
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
;
Lei, Min
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Cardiac glycosides
Cinobufagin
Natural product
Cytotoxicity
Antiproliferative activities
Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802
作者:
Lv, Kaikai
;
Chen, Weicong
;
Chen, Danqi
;
Mou, Jie
;
Zhang, Huijie
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/21
Synthesis of oleandrin derivatives and their cytotoxic activity
期刊论文
STEROIDS, 2020, 卷号: 159, 页码: 7
作者:
Zhang, Yanzhi
;
Chen, Xubing
;
Zhou, Yang
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Cardiac glycosides
Oleandrin (OL)
Natural product
OL-4 '-yl ester
Cytotoxicity
Design and synthesis of new lenalidomide analogs via Suzuki cross-coupling reaction
期刊论文
ARCHIV DER PHARMAZIE, 2020, 页码: 10
作者:
Xiao, Donghuai
;
Wang, Yu-jie
;
Wang, Han-lin
;
Zhou, Yu-bo
;
Li, Jia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
antitumor
arylboronic acid
lenalidomide
Suzuki cross-coupling
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