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上海药物研究所 [34]
厦门大学 [12]
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山东大学 [5]
合肥物质科学研究院 [5]
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期刊论文 [110]
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The reversal of anti-HER2 resistance in advanced HER2-positive breast cancer using apatinib: two cases reports and literature review
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2022
作者:
He, Libin
;
Shen, Xiabo
;
Liu, Yiyuan
;
Gao, Lu
;
Wu, Jiayi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
Advanced human epidermal growth factor receptor 2-positive breast cancer (advanced HER2-positive breast cancer)
apatinib
case report
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
Ratiometric co-delivery of hydroxychloroquine and calculated low-dose paclitaxel efficiently suppresses tumor growth in hepatocellular carcinoma mouse models in vivo
期刊论文
NANO TODAY, 2022, 卷号: 44
作者:
Wang, Wenbin
;
Sun, Hui
;
Gong, Yan
;
Liu, Xiangsheng
;
Liu, Xiao
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2022/12/23
Ratiometric co-delivery
Autophagy
Hepatocellular carcinoma
Chemo-immunotherapy
Hydroxychloroquine
Paclitaxel
The Role of Anti-EGFR Monoclonal Antibody in mCRC Maintenance Therapy
期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 卷号: 9
作者:
Yuan, Meiqin
;
Wang, Zeng
;
Lv, Wangxia
;
Pan, Hongming
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  |  
浏览/下载:20/0
  |  
提交时间:2022/05/16
mCRC
maintenance therapy
EGFR
monoclonal antibody
panitumumab
cetuximab
Efficacy and Safety of Recombinant Human-Mouse Chimeric Anti-CD20 Monoclonal Antibody (SCT400) Combined with CHOP in Patients with Treatment-Naive Diffuse Large B-Cell Lymphoma: A Multicenter, Randomized, Single-Blind, Parallel Active-Controlled, Phase III Study
期刊论文
BLOOD, 2021, 卷号: 138
作者:
Shi, Yuankai
;
Zhang, Qing Yuan
;
Hong, Xiaonan
;
Wang, Zhen
;
Gao, Yuhuan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/12/23
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9
作者:
Chen, Yuning
;
Zhang, Ya-Nan
;
Yan, Renhong
;
Wang, Guifeng
;
Zhang, Yuanyuan
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  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
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  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2021, 卷号: 11, 期号: 4, 页码: 472-479
作者:
Gao, Yuxiong
;
Chen, Zhendong
;
Yang, Changyong
;
Zhong, Dafang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/11/04
Anti-sclerostin monoclonal antibody (SHR-1222)
LC-MS/MS
Anti-drug antibody
Toxicokinetic
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
;
Zhang, Xichen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
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