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上海药物研究所 [5]
武汉大学 [5]
厦门大学 [4]
昆明植物研究所 [3]
上海有机化学研究所 [3]
北京大学 [2]
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期刊论文 [34]
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Cytotoxic androstane derivatives from Sarcococca ruscifolia
期刊论文
FITOTERAPIA, 2020
作者:
Yi, Xin
;
Dai, Zhi
;
Xie, Tian-Zhen
;
Xiao, Xia
;
Liu, Ya-Ping
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/01/05
Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 1, 页码: 239-251
作者:
Omiecinski, Curtis J.
;
Patterson, Andrew D.
;
Smith, Philip B.
;
Tian, Yuan
;
Zhang, Limin
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  |  
浏览/下载:59/0
  |  
提交时间:2019/06/24
NR1I3
constitutive androstane receptor
metabolomics
energy metabolism
Effects of Absence of Constitutive Androstane Receptor on Bile Acid Homeostasis in Male and Female Mice.
期刊论文
Toxicological Sciences, 2019, 卷号: Vol.171 No.1, 页码: 132-145
作者:
Lickteig, Andrew J
;
Zhang, Youcai
;
Klaassen, Curtis D
;
Csanaky, Ivá
;
n L
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  |  
浏览/下载:12/0
  |  
提交时间:2019/11/21
bile acids
biliary excretion
constitutive androstane receptor
muricholic acid
taurocholic acid
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
Prevention of Oxidative Stress by α-Ketoglutarate via Activation of CAR Signaling and Modulation of the Expression of Key Antioxidant-Associated Targets in Vivo and in Vitro
期刊论文
Journal of Agricultural and Food Chemistry, 2018, 卷号: 66, 期号: 43, 页码: 11273–11283
作者:
He, Liuqin
;
Wu, Jian
;
Tang, Wenjie
;
Zhou, Xihong*
;
Lin, Qinlu
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/28
alpha-ketoglutarate
piglets
constitutive androstane receptor
antioxidant enzymes
oxidative stress
Predominant contributions of carboxylesterase 1 and 2 in hydrolysis of anordrin in humans
期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 5, 页码: 533-540
作者:
Jiang, Jinfang
;
Chen, Xiaoyan
;
Zhong, Dafang
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  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Anordiol
anordrin
carboxylesterase
drug-drug interaction
hydrolysis in humans
Discovery of a widespread metabolic pathway within and among phenolic xenobiotics
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Ashrap, Pahriya
;
Zheng, Guomao
;
Wan, Yi
;
Li, Tong
;
Hu, Wenxin
;
Li, Wenjuan
;
Zhang, Hong
;
Zhang, Zhaobin
;
Hu, Jianying
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  |  
浏览/下载:32/0
  |  
提交时间:2017/12/03
triclosan
phenolic xenobiotic
liver microsome
metabolic kinetics
cross-talk reaction
CONSTITUTIVE ANDROSTANE RECEPTOR
REGULATING TRICLOSAN
UNITED-STATES
BISPHENOL-A
METHYL TRICLOSAN
CYTOCHROMES P450
ENZYMES
LIVER
TRICLOCARBAN
INDUCTION
Activation of Constitutive Androstane Receptor Prevents Cholesterol Gallstone Formation.
期刊论文
Am J Pathol, 2017, 卷号: Vol.187 No.4, 页码: 808-818
作者:
Cheng, SH
;
Zou, M
;
Liu, QH
;
Kuang, JY
;
Shen, J
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/02/28
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage
期刊论文
Toxicology Letters, 2017, 卷号: 275, 页码: 67-76
作者:
Cui, Hongmei
;
Gu, Xinsheng
;
Chen, Jingshu
;
Xie, Ying
;
Ke, Sui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
PXR
pregnane X receptor
AhR
aryl hydrocarbon receptor
DRE
dioxin response element
BaP
benzo[a]pyrene
RIF
rifampicin
H2Ax
histone 2Ax
CAR
constitutive androstane receptor
FXR
farnesoid X receptor
CYP450
cytochrome P450
EROD
7-ethoxyresorufin-O-deethylase
PAH
polycyclic aromatic hydrocarbon
ER
estrogen receptor
PXR
AhR
BaP
cyp1a1
DNA damages
Altered Expression of Transporters, its Potential Mechanisms and Influences in the Liver of Rodent Models Associated with Diabetes Mellitus and Obesity
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2016, 卷号: 41, 期号: 3, 页码: 199-210
作者:
Ma, Leilei
;
He, Lei
;
Wang, Le
;
Li, Li
;
Lin, Xuena
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  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
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