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海洋研究所 [10]
西北高原生物研究所 [9]
上海药物研究所 [8]
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期刊论文 [47]
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Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
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  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 152, 页码: 349-358
作者:
Sun, Xueqi
;
Zhang, Jingjing
;
Mi, Yingqi
;
Chen, Yuan
;
Tan, Wenqiang
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/08
STARCH DERIVATIVES
LIGANDS SYNTHESIS
THIOETHER
ANTIFUNGAL
COMPLEXES
Discovery of alkoxy benzamide derivatives as novel BPTF bromodomain inhibitors via structure-based virtual screening
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 86, 页码: 494-500
作者:
Zhang, Dan
;
Han, Jie
;
Lu, Wenchao
;
Lian, Fulin
;
Wang, Jun
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  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Lysine acetylation
Bromodomain
Virtual screening
BPTF inhibitor
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 3683-3692
作者:
Zi, Cheng-Ting
;
Yang, Liu
;
Kong, Qing-Hua
;
Li, Hong-Mei
;
Yang, Xing-Zhi
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  |  
浏览/下载:14/0
  |  
提交时间:2020/03/26
podophyllotoxin
glucoside
synthesis
cytotoxicity
physicochemical properties
Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361
作者:
Jiang, Hao
;
Xing, Jing
;
Wang, Chen
;
Zhang, Hao
;
Yue, Liyan
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  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
Optimization of Release Conditions for Acetylated Amino Sugars from Glycoprotein with the Aid of Experimental Design and Their Sensitive Determination with HPLC
期刊论文
CHROMATOGRAPHIA, 2017
Xia, Lian
;
Liu, Lijie
;
Qu, Fengli
;
Kong, Rongmei
;
Li, Guoliang
;
You, Jinmao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/06/14
Optimization of Release Conditions for Acetylated Amino Sugars from Glycoprotein with the Aid of Experimental Design and Their Sensitive Determination with HPLC
期刊论文
CHROMATOGRAPHIA, 2017
Xia, Lian
;
Liu, Lijie
;
Qu, Fengli
;
Kong, Rongmei
;
Li, Guoliang
;
You, Jinmao
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/07/05
Optimization of Release Conditions for Acetylated Amino Sugars from Glycoprotein with the Aid of Experimental Design and Their Sensitive Determination with HPLC
期刊论文
CHROMATOGRAPHIA, 2017
Xia, Lian
;
Liu, Lijie
;
Qu, Fengli
;
Kong, Rongmei
;
Li, Guoliang
;
You, Jinmao
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/06/21
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