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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Enhanced biological activities of coumarin-functionalized polysaccharide derivatives: Chemical modification and activity assessment
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 253, 页码: 13
作者:
Li, Qing
;
Yang, Yunhui
;
Li, Yijian
;
Mi, Yingqi
;
Ma, Xuanxuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/11/15
Polysaccharide
Chemical modification
Coumarins
Wnt Signaling Pathway Collapse upon beta-Catenin Destruction by a Novel Antimicrobial Peptide SKACP003: Unveiling the Molecular Mechanism and Genetic Activities Using Breast Cancer Cell Lines
期刊论文
MOLECULES, 2023, 卷号: 28, 期号: 3, 页码: 1
作者:
Selvarathinam, Kanitha
;
Subramani, Prabhu
;
Thekkumalai, Malarvili
;
Vilwanathan, Ravikumar
;
Selvarajan, Ramganesh
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/14
antimicrobial peptides
anticancer agents
breast cancer
Wnt pathway
beta-catenin
downregulation
oncology
alternative therapy
Gut microbiota: An emerging therapeutic approach of herbal medicine for prevention of colorectal cancer
期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 卷号: 12
作者:
Ying, Hua-Zhong
;
Xie, Wei
;
Wang, Meng-Chuan
;
He, Jia-Qi
;
Zhang, Huan-Huan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/23
intestinal homeostasis
natural products
chronic inflammation
probiotic
immunoenhancement
tumor microenvironment
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119
作者:
Zhang, Pengge
;
Zhou, Zhixuan
;
Long, Wen
;
Yan, Yuping
;
Li, Youshan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
self-assembly
supramolecular coordination complex
combination chemotherapy
targeted cancer therapy
drug delivery
FK228 sensitizes radioresistant small cell lung cancer cells to radiation
期刊论文
CLINICAL EPIGENETICS, 2021, 卷号: 13
作者:
Li, Hong
;
Ma, Liying
;
Bian, Xing
;
Lv, Yang
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/04/26
Small cell lung cancer
FK228
Histone deacetylase
PI3K
Radioresistance
DNA damage repair
Out-of-the-Box Nanocapsules Packed with On-Demand Hydrophobic Anticancer Drugs for Lung Targeting, Esterase Triggering, and Synergy Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021
作者:
Zhao, Di
;
Jiang, Kai
;
Wang, Yuqi
;
Cheng, Jin
;
Mo, Fangli
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2021/03/15
controllable esterase response
high loading efficiency
lung targeting
multi-drug resistance
universal drug encapsulation
Biomineralized Bacterial Outer Membrane Vesicles Potentiate Safe and Efficient Tumor Microenvironment Reprogramming for Anticancer Therapy
期刊论文
ADVANCED MATERIALS, 2020, 页码: 14
作者:
Qing, Shuang
;
Lyu, Chengliang
;
Zhu, Li
;
Pan, Chao
;
Wang, Shuang
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/03/29
bacterial outer membrane vesicles
biomineralization
cancer immunotherapy
tumor microenvironment reprogramming
Calcitriol-Loaded Dual-pH-Sensitive Micelle Counteracts Pro-Metastasis Effect of Paclitaxel in Triple-Negative Breast Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2020, 页码: 12
作者:
Zheng, Zhong
;
Lang, Tianqun
;
Huang, Xin
;
Wang, Guanru
;
Lee, Robert J.
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
breast cancer
calcitriol
metastasis
micelles
pH-sensitive micelles
Laser ablation in liquids for the assembly of Se@Au chain-oligomers with long-term stability for photothermal inhibition of tumor cells
期刊论文
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2020, 卷号: 566
作者:
Cai, Yunyu
;
Zhang, Yajun
;
Ji, Sihan
;
Ye, Yixing
;
Wu, Shouliang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/11/26
Au nanoparticle
Se nanoparticle
Chain-oligomer
Laser ablation
Green synthesis
Photothermal therapy
Directional assembly
Bipolar interaction
Long-term stability
High photothermal transduction efficiency
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