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科研机构
上海药物研究所 [42]
内容类型
期刊论文 [42]
发表日期
2021 [42]
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发表日期:2021
专题:上海药物研究所
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:
Fan, Xinping
;
Luo, Guanghao
;
Huang, Yu S.
收藏
  |  
浏览/下载:216/0
  |  
提交时间:2021/05/24
Cancer genomics
Copy number alterations
Next-generation sequencing
A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors
期刊论文
Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1
作者:
Wang,Yuqi
;
Gong,Xiang
;
Li,Jie
;
Wang,Hong
;
Xu,Xiaoxuan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/12/16
Cancer stem cells
Macrophage
Microvesicle
Nanoparticles
Cabazitaxel
The double faced role of xanthine oxidoreductase in cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Chen, Man-Man
;
Meng, Ling-Hua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/04
xanthine oxidoreductase (XOR)
ROS
uric acid
cancer therapy
Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021, 页码: 25
作者:
Xu, Xiaoxuan
;
Wu, Yao
;
Qian, Xindi
;
Wang, Yuqi
;
Wang, Jiaoying
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/16
cancer therapy
drug delivery
extracellular matrix
nanomedicine
tumor penetration
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
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  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
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