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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan
收藏  |  浏览/下载:30/0  |  提交时间:2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载:24/0  |  提交时间:2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Normoalbuminuric diabetic kidney disease 期刊论文
Frontiers of Medicine, 2017, 卷号: 11, 期号: 3, 页码: 310-318
作者:  Chao Chen;  Chang Wang;  Chun Hu;  Yachun Han;  Li Zhao
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 29302
作者:  Xu, Xiaoxuan;  Zhu, Xuejing;  Ma, Mingming;  Han, Yachun;  Hu, Chun
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Validation of the interstitial fibrosis and tubular atrophy on the new pathological classification in patients with diabetic nephropathy: A single-center study in China 期刊论文
Journal of Diabetes and its Complications, 2016, 卷号: 30, 期号: 3, 页码: 537-541
作者:  Zhu, Xuejing;  Xiong, Xiaofen;  Yuan, Shuguang;  Xiao, Li;  Fu, Xiao
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03
Smad Anchor for Receptor Activation Regulates High Glucose-Induced EMT via Modulation of Smad2 and Smad3 Activities in Renal Tubular Epithelial Cells 期刊论文
Nephron, 2015, 卷号: 130, 期号: 3, 页码: 213-220
作者:  Tang, Wen-bin;  Ling, Guang-hui;  Sun, Lin;  Zhang, Ke;  Zhu, Xuejing
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/03
MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis 期刊论文
Laboratory Investigation, 2015, 卷号: 95, 期号: 7, 页码: 817-832
作者:  Xiao, Li;  Zhou, Xun;  Liu, Fuyou;  Hu, Chun;  Zhu, Xuejing
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Rap1 ameliorates renal tubular injury in diabetic nephropathy. 期刊论文
Diabetes, 2014, 卷号: 63, 期号: 4, 页码: 1366-1380
作者:  Xiao, Li;  Zhu, Xuejing;  Yang, Shikun;  Liu, Fuyou;  Zhou, Zhiguang
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/03
Urinary TWEAK Level as a Marker of Lupus Nephritis Activity in 46 Cases 期刊论文
Journal of Biomedicine and Biotechnology, 2012, 卷号: 2012, 页码: 359647
作者:  Xuejing, Zhu;  Jiazhen, Tan;  Jun, Li;  Xiangqing, Xu;  Shuguang, Yuan
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Low‐dose paclitaxel ameliorates fibrosis in the remnant kidney model by down‐regulating miR‐192 期刊论文
The Journal of Pathology, 2011, 卷号: 225, 期号: 3, 页码: 364-377
作者:  Sun, Lin;  Zhang, Dongshan;  Liu, Fuyou*;  Xiang, Xudong;  Ling, Guanghui
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/03


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