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The dynamic conformational landscape of the protein methyltransferase SETD8 期刊论文
ELIFE, 2019, 卷号: 8, 页码: 76
作者:  Chen, Shi;  Wiewiora, Rafal P.;  Meng, Fanwang;  Babault, Nicolas;  Ma, Anqi
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma 期刊论文
ONCOGENESIS, 2018, 卷号: 7
作者:  Chen, Wei;  Zhang, Hao;  Chen, Zhifeng;  Jiang, Hao;  Liao, Liping
收藏  |  浏览/下载:108/0  |  提交时间:2019/01/08
Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361
作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan
收藏  |  浏览/下载:108/0  |  提交时间:2019/01/08
Discovery of Novel Disruptor of Silencing Telomeric 1-Like (DOTI L) Inhibitors using a Target-Specific Scoring Function for the (S)-Adenosyl-L-methionine (SAM)-Dependent Methyltransferase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 2026-2036
作者:  Wang, Yulan;  Li, Linjuan;  Zhang, Bidong;  Xing, Jing;  Chen, Shijie
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
Bioactivity Focus of alpha-Cyano-4-hydroxycinnamic acid (CHCA) Leads to Effective Multifunctional Aldose Reductase Inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Zhang, Laitao;  Li, Yi-Fang;  Yuan, Sheng;  Zhang, Shijie;  Zheng, Huanhuan
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534
作者:  Chen, Shijie;  Li, Linjuan;  Chen, Yantao;  Hu, Junchi;  Liu, Jingqiu
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 58, 期号: 20, 页码: 8166-8181
作者:  Meng, Fanwang;  Cheng, Sufang;  Ding, Hong;  Liu, Shien;  Liu, Yan
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Identifying Novel Selective Non-Nucleoside DNA Methyltransferase 1 Inhibitors through Docking-Based Virtual Screening 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 21, 页码: 9028-9041
作者:  Chen, Shijie;  Wang, Yulan;  Zhou, Wen;  Li, Shanshan;  Peng, Jianlong
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Metadynamics Simulation Study on the Conformational Transformation of HhaI Methyltransferase: An Induced-Fit Base-Flipping Hypothesis 期刊论文
BIOMED RESEARCH INTERNATIONAL, 2014
作者:  Jin, Lu;  Ye, Fei;  Zhao, Dan;  Chen, Shijie;  Zhu, Kongkai
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08


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