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科研机构
上海药物研究所 [81]
内容类型
期刊论文 [78]
会议论文 [3]
发表日期
2021 [2]
2020 [4]
2019 [2]
2018 [7]
2017 [2]
2016 [5]
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Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Liang, Xiaoying
;
Lan, Yuan
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
Single site Fe on the (110) surface of gamma-Al2O3: insights from a DFT study including the periodic boundary approach
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 卷号: 23, 期号: 12, 页码: 7164-7177
作者:
Gu, Jiande
;
Wang, Jing
;
Leszczynski, Jerzy
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  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
Single Fe Site on the Surface of gamma-Al2O3: Insights from Density Functional Theory Periodic Boundary Approach
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY C, 2020, 卷号: 124, 期号: 38, 页码: 20931-20941
作者:
Gu, Jiande
;
Wang, Jing
;
Leszczynski, Jerzy
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  |  
浏览/下载:19/0
  |  
提交时间:2020/12/21
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Revelation of AbfR in regulation of mismatch repair and energy metabolism in S. epidermidis by integrated proteomic and metabolomic analysis
期刊论文
JOURNAL OF PROTEOMICS, 2020, 卷号: 226, 页码: 10
作者:
Gu, Lei
;
Liu, Xing
;
Wang, Yu-Qiu
;
Zhou, Yan-ting
;
Zhu, Hong-wen
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/21
Staphylococcus epidermidis
AbfR transcription factor
Oxidation-sensing regulator
Oxidative stress
TMT10-plex labelling
Antibiotic resistance regulator
Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability in A549 cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Liu, Yi
;
Zhu, Ke-xin
;
Cao, Lei
;
Xie, Zhi-fu
;
Gu, Min
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
berberine
anticancer
membrane permeability
apoptosis
mitochondria
Inhibition of MAPK/ERK pathway promotes oligodendrocytes generation and recovery of demyelinating diseases
期刊论文
GLIA, 2019, 卷号: 67, 期号: 7, 页码: 1320-1332
作者:
Suo, Na
;
Guo, Yu-e
;
He, Bingqing
;
Gu, Haifeng
;
Xie, Xin
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  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
differentiation
ERK
MAPK
MEK inhibitor
myelin
oligodendrocyte
oligodendrocyte progenitor cell
remyelination
Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo [d] azepin-7-yl)amino)pyrazine core
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 836-838
作者:
Wang, Yueliang
;
Xing, Li
;
Ji, Yinchun
;
Ye, Jiqing
;
Dai, Yang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
AXL Kinase
Pyrazine
Cancer
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice
Sarinfacetamides A and B, Nitrogenous Diterpenoids with Tricyclo[6.3.1.0(1,5)]dodecane Scaffold from the South China Sea Soft Coral Sarcophyton infundibuliforme
期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 9, 页码: 2637-2640
作者:
Ye, Fei
;
Li, Jing
;
Wu, Yu
;
Zhu, Zheng-Dan
;
Mollo, Ernesto
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  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
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