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CORC

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SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17
Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:  Zheng, Wei;  Wang, Zhen;  Jiang, Xiangrui;  Zhao, Qingjie;  Shen, Jingshan
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong
收藏  |  浏览/下载：37/0  |  提交时间：2020/12/21
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 281-294
作者:  Xing, Jing;  Zhang, Rukang;  Jiang, Xiangrui;  Hu, Tianwen;  Wang, Xinjun
收藏  |  浏览/下载：88/0  |  提交时间：2019/01/08
Astemizole Arrests the Proliferation of Cancer Cells by Disrupting the EZH2-EED Interaction of Polycomb Repressive Complex 2 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 57, 期号: 22, 页码: 9512-9521
作者:  Kong, Xiangqian;  Chen, Limin;  Jiao, Lianying;  Jiang, Xiangrui;  Lian, Fulin
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 17, 页码: 4944-4947
作者:  Gong, Xudong;  Wang, Guan;  Ren, Jing;  Liu, Zheng;  Wang, Zhen
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Design, Synthesis, and Pharmacological Evaluation of Monocyclic Pyrimidinones as Novel Inhibitors of PDE5 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 23, 页码: 10540-10550
作者:  Wang, Guan;  Liu, Zheng;  Chen, Tiantian;  Wang, Zhen;  Yang, Huaiyu
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
A New and Improved Process for N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2012, 卷号: 16, 期号: 12, 页码: 1970-1973
作者:  Mao, Yongjun;  Liu, Zheng;  Yang, Xiaojun;  Xia, Xiangfei;  Zhang, Rongxia
收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08
SYNTHESIS OF N-(3-CYANO-7-ETHOXY-1,4-DIHYDRO-4-OXOQUINOLIN-6-YL)ACETAMIDE 期刊论文
HETEROCYCLES, 2011, 卷号: 83, 期号: 12, 页码: 2851-+
作者:  Zhang, Qiang;  Mao, Yongjun;  Liu, Zheng;  Xie, Kai;  Zhu, Yi
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08

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