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Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 8
作者:  Wang, Yu-zhe;  Yang, De-hua;  Wang, Ming-wei
收藏  |  浏览/下载:22/0  |  提交时间:2021/11/04
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载:41/0  |  提交时间:2021/08/17
alpha-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 9, 页码: 4562-4578
作者:  Zhang, Linlin;  Lin, Daizong;  Kusov, Yuri;  Nian, Yong;  Ma, Qingjun
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis 期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:  Zhang, Zi-jia;  Wu, Wen-yong;  Hou, Jin-jun;  Zhang, Lin-lin;  Li, Fei-fei
收藏  |  浏览/下载:49/0  |  提交时间:2020/07/01
High-throughput screening campaign identifies a small molecule agonist of the relaxin family peptide receptor 4 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Lin, Guang-yao;  Lin, Lin;  Cai, Xiao-qing;  Dai, An-tao;  Zhu, Yue
收藏  |  浏览/下载:27/0  |  提交时间:2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming
收藏  |  浏览/下载:77/0  |  提交时间:2020/07/01
Integrating yeast chemical genomics and mammalian cell pathway analysis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1245-1255
作者:  Zhou, Fu-lai;  Li, Sheena C.;  Zhu, Yue;  Guo, Wan-jing;  Shao, Li-jun
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Extending the Structural View of Class B GPCRs 期刊论文
TRENDS IN BIOCHEMICAL SCIENCES, 2017, 卷号: 42, 期号: 12, 页码: 946-960
作者:  de Graaf, Chris;  Song, Gaojie;  Cao, Can;  Zhao, Qiang;  Wang, Ming-Wei
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 24, 页码: 9865-9881
作者:  Yin, Yanting;  de Waal, Parker W.;  He, Yuanzheng;  Zhao, Li-Hua;  Yang, Dehua
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators 期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
作者:  Song, Gaojie;  Yang, Dehua;  Wang, Yuxia;  de Graaf, Chris;  Zhou, Qingtong
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08


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