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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade 期刊论文 EMBO JOURNAL, 2021, 页码: 16 作者:  Wang, Xu;  Ni, Jiahui;  You, Yan;  Feng, Guize;  Zhang, Sulin 收藏  |  浏览/下载：37/0  |  提交时间：2021/12/16 E-cadherin  IBD  intestinal barrier function  LPS release  SNX10   A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8 作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan 收藏  |  浏览/下载：72/0  |  提交时间：2021/11/04 chimmitecan  mass spectrometry  pharmacokinetics  simmitecan  solid tumors   Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11 作者:  Bao, Weilian;  Liu, Xiaohong;  You, Yan;  Hou, Hui;  Wang, Xu 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/16 SNX10  IBD  Macrophage  PIKfyve  TBK1  PPI inhibitor   SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：79/0  |  提交时间：2021/08/17 Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2 期刊论文 BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197 作者:  Wu, Wenjun;  Wang, Weige;  Franzen, Carrie A.;  Guo, Hui;  Lee, Jimmy 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models 期刊论文 AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645 作者:  Wang, Lei;  Zhu, Xi;  Li, Lili;  Li, Lin;  Fu, Li 收藏  |  浏览/下载：77/0  |  提交时间：2021/06/11 PARP  DNA damage  hematologic toxicity  beta-glucuronidase  tumor selectivity