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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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共13条,第1-10条
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发表日期:2021
专题:上海药物研究所
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Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:
Wei, Dan
;
Wang, Hanlin
;
Zeng, Qinghe
;
Wang, Wenjing
;
Hao, Bingbing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Xiong, Juan
;
Zhou, Peng-Jun
;
Jiang, Hao-Wen
;
Huang, Ting
;
He, Yu-Hang
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
forrestiacids
lipogenesis inhibitors
natural products
structure elucidation
terpenoids
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/08/17
Four new diterpenoids from the twigs and leaves of Phyllanthus acidus
期刊论文
TETRAHEDRON, 2021, 卷号: 91, 页码: 6
作者:
Yuan, Yu-Rong
;
Li, Yan-Wen
;
Huang, Yi-Qi
;
Liu, Qun-fang
;
Ren, Yu-Hao
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
Phyllanthus acidus
Cleistanthane-type diterpenoid
ECD calculation
Biosynthetic pathway
Cytotoxicity
Cinnacetals A and B: Two highly oxidated and modified isoryanodane diterpenoids from Cinnamomum cassia
期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 5
作者:
Huang, Yi-Qi
;
Zhou, Bin
;
Yuan, Yu-Rong
;
Ren, Yu-Hao
;
Li, Dong-Li
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/08/17
Cinnamomum cassia
Isoryanodane diterpenoid
X-ray crystallography
ECD calculation
Biosynthetic pathway
A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9
作者:
Li, Zhen-wei
;
Wei, Wen-long
;
Li, Hao-jv
;
Wu, Shi-fei
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/05/24
Metabolite profiling
Solid-phase extraction
Mass defect filter
Precursor ion list
Danqi Tongmai tablet
Rh-Catalyzed cascade C-H activation/C-C cleavage/cyclization of carboxylic acids with cyclopropanols
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:
Wang, Siqi
;
Miao, Erfei
;
Wang, Hao
;
Song, Bichao
;
Huang, Wei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
In vitro studies of deferasirox derivatives as potential organelle-targeting traceable anti-cancer therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 页码: 4
作者:
Steinbrueck, Axel
;
Sedgwick, Adam C.
;
Han, Hai-Hao
;
Zhao, Michael Y.
;
Sen, Sajal
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/06/11
An enhanced strategy integrating offline superimposed two-dimensional separation with mass defect filter and diagnostic ion filter: Comprehensive characterization of steroid alkaloids in Fritillariae Pallidiflorae Bulbus as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1643, 页码: 10
作者:
An, Ya-ling
;
Wei, Wen-long
;
Li, Hao-jv
;
Li, Zhen-wei
;
Yao, Chang-liang
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/05/24
Mass defect filter
Diagnostic ion filter
Comprehensive characterization
Steroid alkaloids
Fritillariae Pallidiflorae Bulbus
Offline superimposed two-dimensional separation
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
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