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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：42/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain 期刊论文 MOLECULAR BRAIN, 2021, 卷号: 14, 期号: 1, 页码: 22 作者:  Shao, Fang-bing;  Fang, Jun-fan;  Wang, Si-si;  Qiu, Meng-ting;  Xi, Dan-ning 收藏  |  浏览/下载：112/0  |  提交时间：2021/11/04 Chronic inflammatory pain  Anxiety-like behavior  GABAergic system  Anterior cingulate cortex  synaptic transmission   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor   Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Chemical profiling of Huashi Baidu prescription, an effective anti-COVID-19 TCM formula, by UPLC-Q-TOF/MS 期刊论文 CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 6, 页码: 473-480 作者:  Wei Wen-Long;  Wu Shi-Fei;  Li Hao-Jv;  Li Zhen-Wei;  Qu Hua 收藏  |  浏览/下载：20/0  |  提交时间：2021/08/17 Huashi Baidu prescription  Corona virus disease 2019  Characterization of chemical constituents  ELISA   A systematic strategy integrating solid-phase extraction, full scan range splitting, mass defect filter and precursor ion list for comprehensive metabolite profiling of Danqi Tongmai tablet in rats 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 9 作者:  Li, Zhen-wei;  Wei, Wen-long;  Li, Hao-jv;  Wu, Shi-fei;  Huang, Yong 收藏  |  浏览/下载：81/0  |  提交时间：2021/05/24 Metabolite profiling  Solid-phase extraction  Mass defect filter  Precursor ion list  Danqi Tongmai tablet   Characteristic Malonyl Ginsenosides from the Leaves of Panax notoginseng as Potential Quality Markers for Adulteration Detection 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4849-4857 作者:  Yao, Chang-liang;  Wang, Jing;  Li, Zhen-wei;  Qu, Hua;  Pan, Hui-qin 收藏  |  浏览/下载：57/0  |  提交时间：2021/08/17 adulteration  Panax notoginseng leaves  malonyl ginsenosides  quality markers   An enhanced strategy integrating offline superimposed two-dimensional separation with mass defect filter and diagnostic ion filter: Comprehensive characterization of steroid alkaloids in Fritillariae Pallidiflorae Bulbus as a case study 期刊论文 JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1643, 页码: 10 作者:  An, Ya-ling;  Wei, Wen-long;  Li, Hao-jv;  Li, Zhen-wei;  Yao, Chang-liang 收藏  |  浏览/下载：50/0  |  提交时间：2021/05/24 Mass defect filter  Diagnostic ion filter  Comprehensive characterization  Steroid alkaloids  Fritillariae Pallidiflorae Bulbus  Offline superimposed two-dimensional separation   SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu 收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24 SL010110  gluconeogenesis  primary mouse hepatocytes  PEPCK1  acetylation  degradation   Two New Aristolochic Acid Analogues from the Roots of Aristolochia contorta with Significant Cytotoxic Activity 期刊论文 MOLECULES, 2021, 卷号: 26, 期号: 1, 页码: 11 作者:  Ji, Hong-Jian;  Li, Jia-Yuan;  Wu, Shi-Fei;  Wu, Wen-Yong;  Yao, Chang-Liang 收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24 Aristolochia contorta  aristolochic acid  cytotoxicity  molecular docking