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浏览/检索结果: 共28条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11 作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong 收藏  |  浏览/下载：81/0  |  提交时间：2021/12/16 covalent modification  probes  proteome  LC3  post-translational modification   Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11 作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian 收藏  |  浏览/下载：101/0  |  提交时间：2021/11/04 Anti-inflammatory activity  TNF alpha  ER beta  IBD Arylisoquinolones   5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Unusual polyoxygenated casbane diterpenoids from the South China Sea soft coral Sinularia erecta 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 8 作者:  Liu, Jiao;  Wu, Meng-Jun;  Li, Heng;  Wang, Hong;  Tang, Wei 收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04 Soft coral  Sinularia erecta  Casbane  Stereochemistry  Anti-inflammatory activity   Ketamine activated glutamatergic neurotransmission by GABAergic disinhibition in the medial prefrontal cortex 期刊论文 NEUROPHARMACOLOGY, 2021, 卷号: 194, 页码: 10 作者:  Zhang, Bing;  Yang, Xili;  Ye, Luyu;  Liu, Rui;  Ye, Binglu 收藏  |  浏览/下载：20/0  |  提交时间：2021/08/17 Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng 收藏  |  浏览/下载：47/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine   Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12 作者:  Rao, Danni;  Li, Heng;  Ren, Xuelian;  Sun, Yaoliang;  Wen, Cuiyun 收藏  |  浏览/下载：28/0  |  提交时间：2021/08/17 Zeta-chain associated protein kinase 70 kDa (ZAP-70)  Covalent inhibitor  T cell  Autoimmune diseases   Neolinulicin A and B from Inula japonica and their anti-inflammatory activities 期刊论文 FITOTERAPIA, 2021, 卷号: 152, 页码: 6 作者:  Wu, Rui-fang;  Zhou, Bing-duo;  Wang, Wen-qiong;  Chen, Tong;  Xu, Ting-ting 收藏  |  浏览/下载：18/0  |  提交时间：2021/08/17 Inula japonica  Sesquiterpenes  Anti-inflammation   Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7 作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian 收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17 Nur77  Binding site evaluation  Virtual Screening  Inflammation   Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14 作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei 收藏  |  浏览/下载：40/0  |  提交时间：2021/08/17 SHP2 degradation  Proteolysis targeting chimera (PROTAC)  Thalidomide-based heterobifunctional molecules  E3 ubiquitin ligase  CRBN