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科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2020 [13]
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发表日期:2020
专题:上海药物研究所
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Ruthenium-Catalyzed C-H Activations for the Synthesis of Indole Derivatives
期刊论文
CATALYSTS, 2020, 卷号: 10, 期号: 11, 页码: 27
作者:
Zhu, Haoran
;
Zhao, Sen
;
Zhou, Yu
;
Li, Chunpu
;
Liu, Hong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/05/24
ruthenium
C-H activation
indole
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP
Structurally diverse halosesquiterpenoids from the red alga Laurencia composita Yamada
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Hu, Zhi-Biao
;
Yu, Xiao-Qing
;
Wang, Bin
;
Liu, Ai-Hong
;
Zhao, Tian-Sheng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Laurencia composita
Chamigrane sesquiterpenoids
Bisabolane sesquiterpenoids
Nerolidol derivative
Modified Mosher's method
Antifungal activity
Antibacterial activity
Comparative Transcriptomic and Proteomic Analyses Prove that IFN-lambda 1 is a More Potent Inducer of ISGs than IFN-alpha against Porcine Epidemic Diarrhea Virus in Porcine Intestinal Epithelial Cells
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 9, 页码: 3697-3707
作者:
Zhao, Mingzhi
;
Li, Liang
;
Zhai, Linhui
;
Yue, Qi
;
Liu, Hongyu
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2020/12/21
intestinal epithelial cell
IFN-lambda 1
IFN-alpha
anti-PEDV
transcriptomics
proteomics
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Integrative Proteomic Characterization of Human Lung Adenocarcinoma
期刊论文
CELL, 2020, 卷号: 182, 期号: 1, 页码: 245-+
作者:
Xu, Jun-Yu
;
Zhang, Chunchao
;
Wang, Xiang
;
Zhai, Linhui
;
Ma, Yiming
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors
期刊论文
NATURE, 2020, 页码: 24
作者:
Jin, Zhenming
;
Du, Xiaoyu
;
Xu, Yechun
;
Deng, Yongqiang
;
Liu, Meiqin
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:
Zhao, Shuang
;
Zhu, Yan-Yan
;
Wang, Xiao-Yu
;
Liu, Yong-Sheng
;
Sun, Yun-Xiang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
SIRT6
inhibitor
nature molecule
molecular dynamics simulation
scutellarin
hydrophobic interactions
pi-stacking interactions
binding sites
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