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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2020    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice 期刊论文 ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56 作者:  Xu, Xiaoju;  Xu, Xu;  Hao, Yanping;  Zhu, Xialin;  Lu, Jian 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition 期刊论文 BIOMATERIALS, 2020, 卷号: 257, 页码: 13 作者:  Wang, Kaiyuan;  Ye, Hao;  Zhang, Xuanbo;  Wang, Xia;  Yang, Bin 收藏  |  浏览/下载：43/0  |  提交时间：2020/12/24 Exosome membrane  Cucurbitacin B  Paclitaxel  Breast cancer metastasis  Programmable bioactivation   Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992 作者:  Song, Bichao;  Xie, Peipei;  Li, Yingzi;  Hao, Jiping;  Wang, Lu 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文 ADVANCED SCIENCE, 2020, 页码: 13 作者:  Sun, Zhongya;  Zhang, Hao;  Zhang, Yuanyuan;  Liao, Liping;  Zhou, Wen 收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 8 作者:  Chen, Lu;  Quan, Haitian;  Xu, Zhongliang;  Wang, Hao;  Xia, Yuanzhi 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats 期刊论文 NEUROSCIENCE BULLETIN, 2020, 卷号: 36, 期号: 4, 页码: 333-345 作者:  Gu, Pan;  Xu, Zi-Hao;  Cao, Yu-Ze;  Liao, Sheng-Hui;  Deng, Qian-Fang 收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 Epilepsy  Synchrotron radiation  3D  Angioarchitecture  Blood vessel  Remodeling   The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui 收藏  |  浏览/下载：46/0  |  提交时间：2020/07/01 immunomodulatory drugs (IMiDs)  CC-885  BNIP3L  mitophagy  CRBN  acute myeloid leukemia  mitochondria-targeting drugs   Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292 作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells