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Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants 期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:  Mao, Xiao-Yuan*;  Jin, Ming-Zhu;  Chen, Jin-Fei*;  Zhou, Hong-Hao;  Jin, Wei-Lin*
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/03
PD  Parkinson's disease  AD  Alzheimer's disease  EGCG  (−)-Epigallocatechin-3-gallate  NRF2  NF-E2-related factor 2  ROS  reactive oxygen species  H2O2  hydrogen peroxide  ER  endoplasmic reticulum  GPX  glutathione-peroxidase  NOX  NADPH oxidases (NOXs)  LOX  lipoxygenases  ERK  extracellular signal-regulated kinase  JNK  c-Jun amino-terminal kinase  MAPK  mitogen-activated protein kinase  HNE  4-hydroxy-2-nonenol  ARE  antioxidant responsive element  GST  glutathione S-transferase  IFNγ  interferon-γ  LPS  lipopolysaccharide  SOD  superoxide dismutase  TNF-α  tumor necrosis factor-α  APP  β-amyloid precursor protein  SAM  S-adenosylmethionine  MAT  methionine adenosyltransferase  SAH  Sadenosyl homocysteine  MT  methyltransferases  BDNF  brain-derived neurotrophic factor  Nutraceuticals  Neuroprotection  Anti-cancer  ROS addiction  Ferroptosis  Oxidative stress  
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling 期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:  Liu, Jianxin;  Tang, Jinshan;  Zuo, Yihan;  Yu, Yang;  Luo, Pei
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/03
NO  nitric oxide  PGE2  prostaglandin E2  NSAIDs  non-steroidal anti-inflammatory drugs  qRT-PCR  quantitative real-time polymerase chain reaction  LPS  lipopolysaccharide  IFN-γ  interferon γ  G-CSF  granulocyte colony stimulating factor  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  IL-6  interleukin-6  MCP-1  monocyte chemoattractant protein-1  NF-κB  Nuclear factor-κB  IκB  inhibitory protein  IKK  IκB kinase  RPS3  ribosomal protein S3  iNOS  inducible nitric oxide synthase  COX-2  cyclooxygenase-2  PGESs  prostaglandin E2 synthases  mPGES-1  microsomal prostaglandin synthetase-1  mPGES-2  microsomal prostaglandin E synthase-2  cPGES  cytosolic prostaglandin E synthase  MAPK  mitogen-activated protein kinases  ERK  extracellular signal-regulated kinase  JNK  c- Jun N-terminal kinase  PGI2  prostacyclin I2  PGD2  prostaglandin D2  PGF2α  prostaglandin F2α  TXA2  thromboxane A2  Stauntoside B (PubChem CID: 101010462)  Stauntoside B  Cynanchi stauntonii  Lipopolysaccharide  Anti-inflammatory activity  NF-κB  MAPK  
Roles of 1,25(OH)(2)D-3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4(+) T Cells and the PKC delta/ERK Signaling Pathway 期刊论文
Cellular Physiology and Biochemistry, 2016, 卷号: 40, 期号: 3-4, 页码: 743-756
作者:  He, Xiao-Jie*;  Ding, Yan;  Xiang, Wei;  Dang, Xi-Qiang
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/03
CTGF enhances resistance to 5-FU-mediating cell apoptosis through FAK/MEK/ERK signal pathway in colorectal cancer 期刊论文
OncoTargets and Therapy, 2016, 卷号: 9, 页码: 7285-7295
作者:  Yang, Kai;  Gao, Kai;  Hu, Gui;  Wen, Yanguang;  Lin, Changwei
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
The effect of Chaihu-Shugan-San and its components on the expression of ERK5 in the hippocampus of depressed rats 期刊论文
Journal of Ethnopharmacology, 2014, 卷号: 152, 期号: 2, 页码: 320-326
作者:  Qiu, Juan*;  Hu, Sui-Yu;  Zhang, Chun-Hu;  Shi, Guang-Qing;  Wang, Su-e
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/03
Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014, 卷号: 1843, 期号: 3, 页码: 618-628
作者:  Sun, Ting Ting;  Wang, Yan;  Cheng, Hong;  Zhang, Xiao Hu;  Xiang, Juan Juan
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Neuroprotective and anti-apoptotic effects of valproic acid on adult rat cerebral cortex through ERK and Akt signaling pathway at acute phase of traumatic brain injury 期刊论文
Brain Research, 2014, 卷号: 1555, 页码: 1-9
作者:  Zhang, Chi;  Zhu, Jie;  Zhang, Jing;  Li, Haoyu;  Zhao, Zijin
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03
Activation of spinal ERK1/2 contributes to mechanical allodynia in a rat model of postoperative pain 期刊论文
Molecular Medicine Reports, 2013, 卷号: 7, 期号: 5, 页码: 1661-1665
作者:  Shi, Xu-Dan;  Fu, Di;  Xu, Jun-Mei;  Zhang, Yan-Ling*;  Dai, Ru-Ping
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Analgesic effects of the COX-2 inhibitor parecoxib on surgical pain through suppression of spinal ERK signaling 期刊论文
Experimental and Therapeutic Medicine, 2013, 卷号: 6, 期号: 1, 页码: 275-279
作者:  Gu, Ya-Jing;  Shi, Xu-Dan;  Fu, Di;  Yang, Yong*;  Wang, Ya-Ping
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/03

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