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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 专题：中南大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文 Redox Biology, 2018, 卷号: 16, 页码: 32-46 作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui 收藏  |  浏览/下载：30/0  |  提交时间：2019/12/03 ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ   Survivin-targeting miR-542-3p overcomes HER3 signaling-induced chemoresistance and enhances the antitumor activity of paclitaxel against HER2-overexpressing breast cancer 期刊论文 Cancer Letters, 2018, 卷号: 420, 页码: 97-108 作者:  Lyu, Hui;  Wang, Shuiliang;  Huang, Jingcao;  Wang, Bolun;  He, Zhimin 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03 HER3  Survivin  miRNA  Paclitaxel resistance  Breast cancer  RTKs  Receptor tyrosine kinases  PI-3K  Phosphoinositide 3-kinase  CHX  Cycloheximide  ELISA  Enzyme-linked immunosorbent assay  IHC  Immunohistochemistry  i.p.  Intraperitoneal   Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文 Redox Biology, 2017, 卷号: 13, 页码: 482-497 作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao 收藏  |  浏览/下载：24/0  |  提交时间：2019/12/03 DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc   MiR-124 down-regulation is critical for cancer associated fibroblasts-enhanced tumor growth of oral carcinoma 期刊论文 Experimental Cell Research, 2017, 卷号: 351, 期号: 1, 页码: 100-108 作者:  Li, Xia*;  Fan, Qinqiao;  Li, Jinyun;  Song, Jing;  Gu, Yangcong 收藏  |  浏览/下载：8/0  |  提交时间：2019/12/03 CAFs  Cancer associated fibroblasts  NFs  normal fibroblasts  OC  Oral cancer or (OCC), oral cancer cells  C-C motif  Chemokine ligand 2 (CCL2)  IL-8  Interleukin 8  OSCC  Oral squamous cell carcinoma  CM  Conditional medium  IHC  Immunohistochemistry  Cancer associated fibroblasts (CAFs)  MiR-124  Chemokine (C-C motif) ligand 2  Interleukin 8  Oral squamous cell carcinoma   BMP4 promotes metastasis of hepatocellular carcinoma by an induction of epithelial–mesenchymal transition via upregulating ID2 期刊论文 Cancer Letters, 2017, 卷号: 390, 期号: Volume 390, 页码: 67-76 作者:  Zeng, Shan;  Zhang, Yan;  Ma, Junli;  Deng, Ganlu;  Qu, Yanlin 收藏  |  浏览/下载：11/0  |  提交时间：2019/12/03 Bone morphogenetic protein 4  Epithelial–mesenchymal transition  Hepatocellular carcinoma  Metastasis  ID2  AFP  alpha-fetoprotein  ANLT  adjacent non-tumorous liver tissue  BMP4  Bone morphogenetic protein 4  EMT  epithelial–mesenchymal transition  GAPDH  glyceraldehyde-3-phosphate dehydrogenase  HCC  hepatocellular carcinoma  ID2  the inhibitor of DNA binding 2  IHC  immunohistochemistry  MMP  matrix metalloproteinase  OS  overall survival  RFS  recurrence free survival  RFA  radiofrequency ablation  shRNA  short-hairpin RNA  siRNA  short interfering RNA  TACE  transarterial chemoembolization  TNM  tumor-node-metastasis   BMP4 promotes oxaliplatin resistance by an induction of epithelial-mesenchymal transition via MEK1/ERK/ELK1 signaling in hepatocellular carcinoma 期刊论文 Cancer Letters, 2017, 卷号: 411, 页码: 117-129 作者:  Ma, Junli;  Zeng, Shan;  Zhang, Yan;  Deng, Ganlu;  Qu, Yanling 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/03 Bone morphogenetic protein 4  Epithelial-mesenchymal transition  ELK1  Hepatocellular carcinoma  Oxaliplatin  AFP  alpha-fetoprotein  ANLT  adjacent non-tumorous liver tissue  BMP4  Bone morphogenetic protein 4  DCR  disease control rate  EMT  epithelial-mesenchymal transition  HCC  hepatocellular carcinoma  IHC  immunohistochemistry  MMP  matrix metalloproteinase  OS  overall survival  PFS  progression free survival  RFA  radiofrequency ablation  RR  Response rate  siRNA  short interfering RNA  TACE  transarterial chemoembolization  TUNEL  TdT-mediated dUTP nick end-labeling   Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer's disease. 期刊论文 Neuroscience, 2016, 卷号: 336, 期号: Volume 336, 页码: 81-101 作者:  Griffith, Chelsea M.;  Xie, Mi-Xin;  Qiu, Wen-Ying;  Sharp, Andrew A.;  Ma, Chao 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/03 AD  Alzheimer’s disease  ALV  alveus  Aβ  beta amyloid  CNS  central nervous system  DAB  diaminobenzidine  GAPDH  glyceraldehyde-3-phosphate  GFAP  glial fibrillary protein  GS  glutamine synthetase  HH3  phosphorylated histone H3  IHC  immunohistochemistry  IR  immunoreactivity  Kir  inwardly rectifying potassium channel  SO  stratum oriens  SP  stratum pyramidale  SR  stratum radiatum  SUR  sulfonylurea  astrogliosis  CA1  GFAP  inwardly rectifying potassium channels  Kir6.1  glutamine synthetase   Salt-inducible Kinase (SIK1) regulates HCC progression and WNT/β-catenin activation 期刊论文 Journal of Hepatology, 2016, 卷号: 64, 期号: 5, 页码: 1076-1089 作者:  Qu, Chao;  He, De;  Lu, Xiaoling;  Dong, Lihua;  Zhu, Yuekun 收藏  |  浏览/下载：15/0  |  提交时间：2019/12/03 ChIP  chromatin immunoprecipitation  DFS  disease-free survival  EGF  epidermal growth factor  EMT  epithelial-mesenchymal transition  GSK-3β  glycogen synthase kinase-3β  HCC  hepatocellular carcinoma  HDAC3  histone deacetylase 3  IF  immunofluorescence  IHC  immunohistochemistry  NCoR  nuclear receptor corepressor  OS  overall survival  PCR  polymerase chain reaction  TBL1  transducin-beta-like protein 1  TBLR1  transducing-beta-like 1 X-linked receptor 1  TF  transcriptional factor  shSIK1  small hairpin RNA targeting SIK1  Salt-inducible kinase 1  Twist1  Epithelial-mesenchymal transition  β-catenin  Silencing mediator for retinoid  Thyroid receptors   PABPC1 interacts with AGO2 and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma 期刊论文 Cancer Letters, 2015, 卷号: 367, 期号: 1, 页码: 49-57 作者:  Zhang, Hui;  Sheng, Cheng;  Yin, Yongjia;  Wen, Shu;  Yang, Guoping 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03 Hepatocellular carcinoma  AGO2  RNA-induced silencing complex  PABPC1  microRNA  Ab  antibodies  AGO2  argonaute 2  eIFG4  eukaryotic initiation factor 4G  G1  well-differentiated  G2  moderately differentiated  G3  poorly differentiated  G4  undifferentiated  HCC  hepatocellular carcinoma  H&E  hematoxylin–eosin  hnRNPs  heterologous nuclear ribonucleoproteins  IHC  immunohistochemistry  IP  immunoprecipitates  KD  PABPC1-knockdown  miRNA  microRNA  MTT  3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide  NAT  normal adjacent tissue  OE  PABPC1-overexpressing  PFA  paraformaldehyde  RIP  RNA immunoprecipitation  RISC  RNA-induced silencing complex  WB  western blot   Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells 期刊论文 Matrix Biology, 2015, 卷号: 47, 页码: 66-84 作者:  Gorski, Daniel J;  Xiao, Wenfeng;  Li, Jun;  Luo, Wei;  Lauer, Mark 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03 A2M  alpha-2-macroglobulin  ADSC  adipose derived stromal cell  Acan  aggrecan  Vcan  versican  CS/DS  chondroitin/dermatan sulfate  DE52  diethyl-amino-ethyl cellulose  ECM  extracellular matrix  HA  hyaluronan  IHC  immunohistochemistry  KO  knockout  LRP1  lipoprotein receptor related protein-1  TGF-β1  transforming growth factor beta-1  BMP7  bone morphogenetic protein 7  TS5  a disintegrin and metalloproteinase with thrombospondin motifs 5  ts5−/−J  TS5 knockout mouse from Jackson Labs  ts5−/−P  TS5 knockout mouse from Lexicon  WT  wild type  ADAMTS5 knock out  ADAMTS5  Aggrecan  Versican  Hyaluronan  Degradation  Adipose derived stromal cells  Mesenchymal stem cells