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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
IncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2018, 卷号: 12, 页码: 741-750
作者:  Wang, Juan;  Pang, Jian;  Li, Huiling;  Long, Jie;  Fang, Fang
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载：24/0  |  提交时间：2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Changes of transforming growth factor beta 1 in patients with type 2 diabetes and diabetic nephropathy: A PRISMA-compliant systematic review and meta-analysis. 期刊论文
Medicine (United States), 2017, 卷号: 96, 期号: 15, 页码: e6583
作者:  Qiao, Yong-Chao;  Chen, Yin-Ling;  Pan, Yan-Hong;  Ling, Wei;  Tian, Fang
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/03
Serum TNF-α concentrations in type 2 diabetes mellitus patients and diabetic nephropathy patients: A systematic review and meta-analysis 期刊论文
Immunology Letters, 2017, 卷号: 186, 页码: 52-58
作者:  Chen, Yin-ling;  Qiao, Yong-chao;  Xu, Yan;  Ling, Wei;  Pan, Yan-hong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Mitochondria: A Novel Therapeutic Target in Diabetic Nephropathy. 期刊论文
Current medicinal chemistry, 2017, 卷号: 24, 期号: 29, 页码: 3185-3202
作者:  Yang, Shikun;  Han, Yachun;  Liu, Jun;  Song, Panai;  Xu, Xiaoxuan
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/03
Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy 期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 10, 页码: e0164135
作者:  Yuan, Fang;  Kolb, Ryan;  Pandey, Gaurav;  Li, Wei;  Sun, Lin
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03
p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 29302
作者:  Xu, Xiaoxuan;  Zhu, Xuejing;  Ma, Mingming;  Han, Yachun;  Hu, Chun
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Validation of the interstitial fibrosis and tubular atrophy on the new pathological classification in patients with diabetic nephropathy: A single-center study in China 期刊论文
Journal of Diabetes and its Complications, 2016, 卷号: 30, 期号: 3, 页码: 537-541
作者:  Zhu, Xuejing;  Xiong, Xiaofen;  Yuan, Shuguang;  Xiao, Li;  Fu, Xiao
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03
Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway 期刊论文
International Journal of Molecular Medicine, 2016, 卷号: 38, 期号: 4, 页码: 1179-1189
作者:  Huang, Guodong;  Lv, Jianzhen;  Li, Tongyu;  Huai, Guoli;  Li, Xiang
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03

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